Protein: IGKC
Immunoglobulin kappa constant (Ig kappa chain C region) (Ig kappa chain C region AG) (Ig kappa chain C region CUM) (Ig kappa chain C region EU) (Ig kappa chain C region OU) (Ig kappa chain C region ROY) (Ig kappa chain C region TI)

Gene: IGKC
Organism: Homo sapiens
Interactions: 107
UniProt ID: P01834

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0003823 - antigen binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

353480

IGHG1
Immunoglobulin heavy constant gamma 1

3

16

Small-scale

0.834

High

353510

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

2

20

Small-scale

0.754

High

353481

IGHG4
Immunoglobulin heavy constant gamma 4

1

16

Small-scale

0.647

High

126323

MATN2
Matrilin-2

1

8

High-throughput

0.575

High

198337

KLK10
Kallikrein-10

1

15

High-throughput

0.575

High

353482

IGHM
Immunoglobulin heavy constant mu

1

16

High-throughput

0.575

High

353484

ALBU
Albumin

1

3

High-throughput

0.575

High

353494

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

4

High-throughput

0.575

High

353522

FNDC1
Fibronectin type III domain-containing protein 1

1

10

High-throughput

0.575

High

353525

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

High-throughput

0.575

High

353541

FNDC5
Fibronectin type III domain-containing protein 5

1

6

High-throughput

0.575

High

353530

HBM
Hemoglobin subunit mu

2

5

High-throughput

0.552

High

353499

CAH8
Carbonic anhydrase-related protein

1

6

High-throughput

0.514

High

353523

LRC10
Leucine-rich repeat-containing protein 10

1

4

High-throughput

0.514

High

353492

ZSC20
Zinc finger and SCAN domain-containing protein 20

2

2

High-throughput

0.504

High

353553

CDK15
Cyclin-dependent kinase 15

2

4

High-throughput

0.504

High

353558

DDX31
ATP-dependent DNA helicase DDX31

2

4

High-throughput

0.504

High

353564

TB22B
TBC1 domain family member 22B

2

3

High-throughput

0.504

High

353515

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

125953

UPK1A
Uroplakin-1a

1

5

High-throughput

0.445

High

134507

FCN1
Ficolin-1

1

2

High-throughput

0.445

High

239686

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

7

High-throughput

0.445

High

328079

SG1D1
Secretoglobin family 1D member 1

1

5

High-throughput

0.445

High

353483

APOA1
Apolipoprotein A-I

1

3

High-throughput

0.445

High

353485

TRFE
Serotransferrin

1

1

High-throughput

0.445

High

353487

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

3

High-throughput

0.445

High

353488

F13B
Coagulation factor XIII B chain

1

4

Small-scale

0.445

High

353489

TAU
Microtubule-associated protein tau

1

1

Small-scale

0.445

High

353491

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.445

High

353493

AATC
Aspartate aminotransferase, cytoplasmic

1

7

High-throughput

0.445

High

353497

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

8

High-throughput

0.445

High

353498

CCR1
C-C chemokine receptor type 1

1

10

High-throughput

0.445

High

353500

TCPZ
T-complex protein 1 subunit zeta

1

1

High-throughput

0.445

High

353502

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

3

High-throughput

0.445

High

353506

GBG10

1

6

High-throughput

0.445

High

353508

STX17
Syntaxin-17

1

4

High-throughput

0.445

High

353518

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

2

Small-scale

0.445

High

353533

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.445

High

353545

ITLN2
Intelectin-2

1

4

High-throughput

0.445

High

353549

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

13

High-throughput

0.445

High

353555

EGFL8
Epidermal growth factor-like protein 8

1

8

High-throughput

0.445

High

353569

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

6

High-throughput

0.445

High

353570

DD19B
ATP-dependent RNA helicase DDX19B

1

3

High-throughput

0.445

High

260431

PITX3
Pituitary homeobox 3

1

4

Small-scale

0.437

High

353486

FRIH
Ferritin heavy chain

1

0

High-throughput

0.426

High

353503

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.426

High

353528

RNLS
Renalase

1

0

Small-scale

0.426

High

353542

NPB
Neuropeptide B

1

0

High-throughput

0.426

High

353543

ATS18
A disintegrin and metalloproteinase with thrombospondin motifs 18

1

0

High-throughput

0.426

High

353548

PMEPA
Protein TMEPAI

1

0

High-throughput

0.426

High

353560

S28A3
Solute carrier family 28 member 3

1

0

Small-scale

0.426

High

353501

MLH1
DNA mismatch repair protein Mlh1

1

1

Small-scale

0.417

High

92431

E9PDS3
Integrin subunit alpha 9

1

4

High-throughput

0.407

High

127086

FOXN3
Forkhead box protein N3

1

2

High-throughput

0.407

High

152477

ENC1
Ectoderm-neural cortex protein 1

1

1

High-throughput

0.407

High

217695

PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

1

2

High-throughput

0.407

High

303618

OR2A4
Olfactory receptor 2A4

1

6

High-throughput

0.407

High

353490

ADT3
ADP/ATP translocase 3

1

7

High-throughput

0.407

High

353495

CCNA2
Cyclin-A2

1

2

High-throughput

0.407

High

353496

PO3F3
POU domain, class 3, transcription factor 3

1

1

High-throughput

0.407

High

353504

PTSS1
Phosphatidylserine synthase 1

1

4

High-throughput

0.407

High

353507

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

2

High-throughput

0.407

High

353509

DSCR6
Protein ripply3

1

3

High-throughput

0.407

High

353511

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

2

High-throughput

0.407

High

353512

SSBP2
Single-stranded DNA-binding protein 2

1

5

High-throughput

0.407

High

353513

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

6

High-throughput

0.407

High

353516

EF1A2
Elongation factor 1-alpha 2

1

2

High-throughput

0.407

High

353517

GABPA
GA-binding protein alpha chain

1

2

High-throughput

0.407

High

353520

UPP1
Uridine phosphorylase 1

1

3

High-throughput

0.407

High

353521

CR021
UPF0711 protein C18orf21

1

6

High-throughput

0.407

High

353524

EMC4
ER membrane protein complex subunit 4

1

4

High-throughput

0.407

High

353526

MYOME
Myomegalin

1

2

High-throughput

0.407

High

353527

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

7

High-throughput

0.407

High

353529

ICE2
Little elongation complex subunit 2

1

1

High-throughput

0.407

High

353531

SFXN4
Sideroflexin-4

1

6

High-throughput

0.407

High

353532

ZN550
Zinc finger protein 550

1

2

High-throughput

0.407

High

353534

KHDC4
KH homology domain-containing protein 4

1

1

High-throughput

0.407

High

353535

CIR1
Corepressor interacting with RBPJ 1

1

6

High-throughput

0.407

High

353536

CERS3
Ceramide synthase 3

1

7

High-throughput

0.407

High

353537

NRSN1
Neurensin-1

1

6

High-throughput

0.407

High

353538

RIBC1
RIB43A-like with coiled-coils protein 1

1

1

High-throughput

0.407

High

353540

ASCC1
Activating signal cointegrator 1 complex subunit 1

1

4

High-throughput

0.407

High

353544

RHBL4
Rhomboid-related protein 4

1

6

High-throughput

0.407

High

353546

TANK
TRAF family member-associated NF-kappa-B activator

1

2

High-throughput

0.407

High

353547

PIGT
GPI transamidase component PIG-T

1

6

High-throughput

0.407

High

353551

SARAF
Store-operated calcium entry-associated regulatory factor

1

4

High-throughput

0.407

High

353554

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

10

High-throughput

0.407

High

353556

FUND2
FUN14 domain-containing protein 2

1

2

High-throughput

0.407

High

353557

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

6

High-throughput

0.407

High

353559

COE2
Transcription factor COE2

1

4

High-throughput

0.407

High

353561

UD110
UDP-glucuronosyltransferase 1A10

1

4

High-throughput

0.407

High

353563

MBNL1
Muscleblind-like protein 1

1

4

High-throughput

0.407

High

353565

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

3

High-throughput

0.407

High

353566

PLK2
Serine/threonine-protein kinase PLK2

1

1

High-throughput

0.407

High

353568

PHF11
PHD finger protein 11

1

7

High-throughput

0.407

High

353571

SSUH2
Protein SSUH2 homolog

1

4

High-throughput

0.407

High

353572

AR2BP
ADP-ribosylation factor-like protein 2-binding protein

1

2

High-throughput

0.407

High

353552

CK5P3
CDK5 regulatory subunit-associated protein 3

1

0

High-throughput

0.249

Low

875

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

263135

SC22B
Vesicle-trafficking protein SEC22b

1

0

High-throughput

0.232

Low

353505

RPIA
Ribose-5-phosphate isomerase

1

0

High-throughput

0.232

Low

353514

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.232

Low

353519

TWF1
Twinfilin-1

1

0

High-throughput

0.232

Low

353539

CCD82
Coiled-coil domain-containing protein 82

1

0

High-throughput

0.232

Low

353550

RNF25
E3 ubiquitin-protein ligase RNF25

1

0

High-throughput

0.232

Low

353562

SHCAF
SIN3-HDAC complex-associated factor

1

0

High-throughput

0.232

Low

353567

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024