Interactor 1: LTOR5 (O43504)
Ragulator complex protein LAMTOR5 (Hepatitis B virus X-interacting protein) (HBV X-interacting protein) (HBX-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5)
Gene: LAMTOR5

Interactor 2: LTOR2 (Q9Y2Q5)
Ragulator complex protein LAMTOR2 (Endosomal adaptor protein p14) (Late endosomal/lysosomal Mp1-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2) (Mitogen-activated protein-binding protein-interacting protein) (MAPBP-interacting protein) (Roadblock domain-containing protein 3)
Gene: LAMTOR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.90 0.880

The method score is based on:

Property Details
Experiments 33961781, 35271311, 22980980, 25567906, 25561175
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LAMTOR5~Robl_LC7
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005765 - lysosomal membrane
GO:0031902 - late endosome membrane
GO:0032008 - positive regulation of TOR signaling
GO:0038202 - TORC1 signaling
and 4 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024