HitPredict

Interactor 1: MED7 (O43513)
Mediator of RNA polymerase II transcription subunit 7 (hMED7) (Activator-recruited cofactor 34 kDa component) (ARC34) (Cofactor required for Sp1 transcriptional activation subunit 9) (CRSP complex subunit 9) (Mediator complex subunit 7) (RNA polymerase transcriptional regulation mediator subunit 7 homolog) (Transcriptional coactivator CRSP33)
Gene: MED7

Interactor 2: CCNC (P24863)
Cyclin-C (SRB11 homolog) (hSRB11)
Gene: CCNC

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016592 - mediator complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 283
+	Hs
		91292 MED7_HUMAN (1-233): 4.09e-115: 330: 100.00		E5RFK5_HUMAN (1-257): 8.34e-74: 229: 100.00
+	Sc
		814156 MED7_YEAST (33-178): 2.43e-39: 137: 32.47		SSN8_YEAST (1-247): 1.48e-54: 181: 27.62
+	Sp
		223910 MED7_SCHPO (77-222): 1.73e-18: 84.8: 27.40		SRB11_SCHPO (1-238): 3.2e-58: 187: 29.58