HitPredict

Interactor 1: WIPF1 (O43516)
WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
Gene: WIPF1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31871319, 11331876
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 503 Hs			1 191
+	Hs
		166043 SYNJ2_HUMAN (11-462): 6.97e-28: 120: 15.62		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		925724 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		1257319 WIPF2_HUMAN (10-503): 6.61e-24: 105: 32.60		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		925226 SOS1_HUMAN (134-459): 8.01e-24: 107: 16.77		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		900553 TGO1_HUMAN (137-399): 6.75e-26: 114: 26.67		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		166039 SYNJ2_HUMAN (11-462): 6.97e-28: 120: 15.62		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		892677 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		894248 WIPF2_HUMAN (10-503): 6.61e-24: 105: 32.60		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		297840 K0754_HUMAN (1-184): 6.54e-09: 61: 10.71		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		867087 SC24C_HUMAN (53-484): 6.03e-11: 67.1: 17.51		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		297823 K0754_HUMAN (1-184): 6.54e-09: 61: 10.71		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		297827 K0754_HUMAN (1-184): 6.54e-09: 61: 10.71		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		297820 K0754_HUMAN (1-184): 6.54e-09: 61: 10.71		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		297812 K0754_HUMAN (1-184): 6.54e-09: 61: 10.71		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		297809 K0754_HUMAN (1-184): 6.54e-09: 61: 10.71		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		297819 K0754_HUMAN (1-184): 6.54e-09: 61: 10.71		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		297834 K0754_HUMAN (1-184): 6.54e-09: 61: 10.71		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82