Interactor 1: LAT (O43561)
Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38)
Gene: LAT

Interactor 2: PTPRJ (Q12913)
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148)
Gene: PTPRJ

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 0.60 0.569

The method score is based on:

Property Details
Experiments 11259588
Identification Methods enzymatic study, biochemical
Interaction Type direct interaction, dephosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001772 - immunological synapse
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0019901 - protein kinase binding
GO:0050852 - T cell receptor signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 262
Hs

1 1337
+ Hs

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Last updated: 15 Jul 2024