HitPredict

Interactor 1: RGS14 (O43566)
Regulator of G-protein signaling 14 (RGS14)
Gene: RGS14

Interactor 2: RAP2A (P10114)
Ras-related protein Rap-2a (EC 3.6.5.2) (RbBP-30)
Gene: RAP2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10926822
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RBD~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 566 Hs			1 183
+	Hs
		207516 RGS14_HUMAN (1-566): 0: 656: 100.00		RAP1A_HUMAN (1-182): 1.35e-81: 241: 61.75
+	Mm
		918978 RGS14_MOUSE (1-545): 0: 594: 87.93		RAB1A_MOUSE (4-183): 5.73e-80: 238: 34.25
+	Mm
		867148 RGS14_MOUSE (1-545): 0: 594: 87.93		RAB2A_MOUSE (4-183): 1.2e-74: 224: 35.36
+	Hs
		207504 RGS14_HUMAN (1-566): 0: 656: 100.00		RASH_HUMAN (1-180): 3.16e-48: 156: 46.49
+	Rn
		139845 RGS12_RAT (16-552): 8.05e-168: 514: 37.46		RASH_RAT (1-180): 3.16e-48: 156: 46.49
+	Hs
		158596 RGS12_HUMAN (3-562): 7.98e-167: 513: 36.61		RASH_HUMAN (1-180): 3.16e-48: 156: 46.49
+	Dm
		442972 RGS_DROME (7-514): 7.23e-131: 418: 28.41		RAP1_DROME (1-165): 8.23e-81: 239: 64.24
+	Dm
		332220 RGS_DROME (7-514): 7.23e-131: 418: 28.41		O96692_DROME (1-177): 8.99e-77: 229: 69.66
+	Dm
		442973 Q9VCX2_DROME (7-514): 1.19e-126: 401: 27.86		RAP1_DROME (1-165): 8.23e-81: 239: 64.24
+	Dm
		332221 Q9VCX2_DROME (7-514): 1.19e-126: 401: 27.86		O96692_DROME (1-177): 8.99e-77: 229: 69.66
+	Hs
		782023 RGS2_HUMAN (53-182): 1.45e-17: 83.6: 37.41		RAP1B_HUMAN (1-182): 4.24e-79: 234: 60.66
+	Hs
		782022 RGS2_HUMAN (53-182): 1.45e-17: 83.6: 37.41		RAB2A_HUMAN (4-183): 2.04e-74: 224: 35.36