HitPredict

Interactor 1: RNF13 (O43567)
E3 ubiquitin-protein ligase RNF13 (EC 2.3.2.27) (RING finger protein 13)
Gene: RNF13

Interactor 2: AP1S2 (P56377)
AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin)
Gene: AP1S2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 381 Hs			1 157
+	Hs
		207565 RNF13_HUMAN (1-381): 6.93e-114: 338: 100.00		AP3S1_HUMAN (1-143): 5.8e-49: 157: 36.91
+	Hs
		207550 RNF13_HUMAN (1-381): 6.93e-114: 338: 100.00		AP3S2_HUMAN (1-143): 4.58e-47: 153: 36.91
+	Hs
		1267489 RN167_HUMAN (15-330): 2.04e-82: 257: 49.54		AP3S1_HUMAN (1-143): 5.8e-49: 157: 36.91
+	Hs
		880422 RN149_HUMAN (43-319): 4.7e-58: 196: 22.85		AP1S2_HUMAN (1-157): 3.42e-55: 172: 100.00