Protein: PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2 (EC 3.6.4.13) (Pre-mRNA-processing protein 2)

Gene: PRP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 67
UniProt ID: P20095

Gene Ontology (top 5):
GO:0000349 - generation of catalytic spliceosome for first transesterification step
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0004386 - helicase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

628197

BRR2
Pre-mRNA-splicing helicase BRR2

5

17

Small-scale

0.910

High

628221

SPP2
Pre-mRNA-splicing factor SPP2

4

0

Small-scale

0.755

High

628217

CWC22
Pre-mRNA-splicing factor CWC22

2

3

High-throughput

0.754

High

628199

PRP8
Pre-mRNA-splicing factor 8

3

8

High-throughput

0.751

High

628227

CEF1
Pre-mRNA-splicing factor CEF1

4

11

High-throughput

0.683

High

628210

PRP17
Pre-mRNA-processing factor 17

2

18

High-throughput

0.675

High

628244

PRP46
Pre-mRNA-splicing factor PRP46

2

17

High-throughput

0.675

High

627828

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

13

High-throughput

0.665

High

628194

PRP19
Pre-mRNA-processing factor 19

3

18

Small-scale

0.646

High

628241

CWC2
Pre-mRNA-splicing factor CWC2

3

11

Small-scale

0.646

High

628202

SN114
Pre-mRNA-splicing factor SNU114

3

11

Small-scale

0.633

High

628187

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

14

High-throughput

0.618

High

628220

RUXF
Small nuclear ribonucleoprotein F

2

6

High-throughput

0.601

High

628214

SF3B1
U2 snRNP component HSH155

3

6

Small-scale

0.586

High

625062

PRP9
Pre-mRNA-splicing factor PRP9

2

1

High-throughput

0.584

High

628188

ISY1
Pre-mRNA-splicing factor ISY1

2

4

High-throughput

0.584

High

628191

PRP45
Pre-mRNA-processing protein 45

2

8

High-throughput

0.584

High

628195

PRP21
Pre-mRNA-splicing factor PRP21

2

1

High-throughput

0.584

High

628204

SLT11
Pre-mRNA-splicing factor SLT11

2

3

High-throughput

0.584

High

628205

NTC20
Pre-mRNA-splicing factor NTC20

2

3

High-throughput

0.584

High

628216

SYF2
Pre-mRNA-splicing factor SYF2

2

3

High-throughput

0.584

High

628228

CWC15
Pre-mRNA-splicing factor CWC15

2

2

High-throughput

0.584

High

628229

SYF1
Pre-mRNA-splicing factor SYF1

2

20

High-throughput

0.584

High

628231

SN309
Pre-mRNA-splicing factor SNT309

2

2

High-throughput

0.584

High

628236

PRP11
Pre-mRNA-splicing factor PRP11

2

2

High-throughput

0.584

High

628242

CLF1
Pre-mRNA-splicing factor CLF1

2

20

High-throughput

0.584

High

628200

NCBP1
Nuclear cap-binding protein complex subunit 1

1

4

High-throughput

0.553

High

628190

BUD31
Pre-mRNA-splicing factor BUD31

2

5

High-throughput

0.533

High

628226

CWC21
Pre-mRNA-splicing factor CWC21

2

2

High-throughput

0.533

High

628213

PRP31
Pre-mRNA-processing factor 31

1

5

High-throughput

0.515

High

628233

LSM6
LSM complex subunit LSM6

1

6

High-throughput

0.515

High

628243

RUXE
Small nuclear ribonucleoprotein E

1

2

High-throughput

0.515

High

628245

RRP12
Ribosomal RNA-processing protein 12

1

4

High-throughput

0.515

High

628198

PRP40
Pre-mRNA-processing protein PRP40

1

7

High-throughput

0.501

High

628234

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.480

High

392209

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.479

High

628192

YJU2
Splicing factor YJU2

1

4

High-throughput

0.479

High

628207

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

8

High-throughput

0.479

High

628208

IST3
U2 snRNP component IST3

1

11

High-throughput

0.479

High

628218

CWC24
Pre-mRNA-splicing factor CWC24

1

3

High-throughput

0.479

High

628222

CUS1
Cold sensitive U2 snRNA suppressor 1

1

2

High-throughput

0.479

High

628232

SMD2
Small nuclear ribonucleoprotein Sm D2

1

4

High-throughput

0.479

High

628246

HSH49
Protein HSH49

1

4

High-throughput

0.479

High

624964

PRP6
Pre-mRNA-splicing factor 6

1

19

High-throughput

0.470

High

628225

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

1

High-throughput

0.470

High

628189

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

1

High-throughput

0.457

High

628206

RSP5
E3 ubiquitin-protein ligase RSP5

1

5

High-throughput

0.457

High

543779

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

628193

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

628196

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

8

High-throughput

0.437

High

628201

URB1
Nucleolar pre-ribosomal-associated protein 1

1

3

High-throughput

0.437

High

628203

ANM1
Protein arginine N-methyltransferase 1

1

5

High-throughput

0.437

High

628209

MSL1
U2 small nuclear ribonucleoprotein B''

1

20

High-throughput

0.437

High

628212

CWC26
Pre-mRNA-splicing factor CWC26

1

2

High-throughput

0.437

High

628223

CWC27
Peptidyl-prolyl isomerase CWC27

1

3

High-throughput

0.437

High

628224

SLU7
Pre-mRNA-splicing factor SLU7

1

2

High-throughput

0.437

High

628230

RSE1
Pre-mRNA-splicing factor RSE1

1

1

High-throughput

0.437

High

628237

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

628238

PML1
Pre-mRNA leakage protein 1

1

2

High-throughput

0.437

High

628239

NCBP2
Nuclear cap-binding protein subunit 2

1

9

High-throughput

0.437

High

628240

RU2A
U2 small nuclear ribonucleoprotein A'

1

7

High-throughput

0.437

High

628219

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.265

Low

628211

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.261

Low

501737

YSF3
RDS3 complex subunit 10

1

0

High-throughput

0.249

Low

628215

TAF4
Transcription initiation factor TFIID subunit 4

1

0

High-throughput

0.249

Low

628235

RDS3
Pre-mRNA-splicing factor RDS3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025