Protein: CLPP
ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) (Caseinolytic protease) (Endopeptidase Clp) (Heat shock protein F21.5) (Protease Ti)

Gene: CLPP
Organism: Escherichia coli K-12
Interactions: 68
UniProt ID: P0A6G7

Gene Ontology (top 5):
GO:0004176 - ATP-dependent peptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

458275

CLPP
ATP-dependent Clp protease proteolytic subunit

5

10

Small-scale

0.938

High

458301

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

4

4

Small-scale

0.902

High

458276

CLPX
ATP-dependent Clp protease ATP-binding subunit ClpX

3

6

Small-scale

0.857

High

457519

CH60
Chaperonin GroEL

2

2

High-throughput

0.612

High

458305

RHO
Transcription termination factor Rho

2

2

High-throughput

0.612

High

370976

KEFC
Glutathione-regulated potassium-efflux system protein KefC

2

0

High-throughput

0.563

High

458303

RRAB
Regulator of ribonuclease activity B

2

0

High-throughput

0.563

High

458279

KPRS
Ribose-phosphate pyrophosphokinase

1

2

High-throughput

0.536

High

458326

KAD
Adenylate kinase

1

2

High-throughput

0.536

High

427784

CHEA
Chemotaxis protein CheA

1

0

High-throughput

0.513

High

458295

TIG
Trigger factor

1

0

High-throughput

0.513

High

458297

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.513

High

458317

RHLE
ATP-dependent RNA helicase RhlE

1

0

High-throughput

0.513

High

458318

BASR
Transcriptional regulatory protein BasR

1

0

High-throughput

0.513

High

356995

RS7
Small ribosomal subunit protein uS7

1

1

High-throughput

0.484

High

448057

NARG
Respiratory nitrate reductase 1 alpha chain

1

1

High-throughput

0.484

High

458278

DNAK
Chaperone protein DnaK

1

2

High-throughput

0.484

High

458282

RL11
Large ribosomal subunit protein uL11

1

1

High-throughput

0.484

High

458283

RL7
Large ribosomal subunit protein bL12

1

1

High-throughput

0.484

High

458284

RL19
Large ribosomal subunit protein bL19

1

1

High-throughput

0.484

High

458289

RS10
Small ribosomal subunit protein uS10

1

1

High-throughput

0.484

High

458298

LON
Lon protease

1

3

High-throughput

0.484

High

458308

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

2

High-throughput

0.484

High

458310

EFTU1
Elongation factor Tu 1

1

2

High-throughput

0.484

High

458313

NARZ
Respiratory nitrate reductase 2 alpha chain

1

1

High-throughput

0.484

High

458322

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.484

High

458325

HLDD
ADP-L-glycero-D-manno-heptose-6-epimerase

1

3

High-throughput

0.484

High

458161

CH10
Co-chaperonin GroES

1

1

High-throughput

0.479

High

356911

RS6
Small ribosomal subunit protein bS6

1

0

High-throughput

0.464

High

445975

T1RK
Type I restriction enzyme EcoKI endonuclease subunit

1

0

High-throughput

0.464

High

458277

GREA
Transcription elongation factor GreA

1

0

High-throughput

0.464

High

458280

RECA
Protein RecA

1

0

High-throughput

0.464

High

458281

RL10
Large ribosomal subunit protein uL10

1

0

High-throughput

0.464

High

458285

RL1
Large ribosomal subunit protein uL1

1

0

High-throughput

0.464

High

458286

RL28
Large ribosomal subunit protein bL28

1

0

High-throughput

0.464

High

458288

RL33
Large ribosomal subunit protein bL33

1

0

High-throughput

0.464

High

458293

METK
S-adenosylmethionine synthase

1

0

High-throughput

0.464

High

458296

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.464

High

458299

RL13
Large ribosomal subunit protein uL13

1

0

High-throughput

0.464

High

458302

GYRA
DNA gyrase subunit A

1

0

High-throughput

0.464

High

458304

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.464

High

458306

RL21
Large ribosomal subunit protein bL21

1

0

High-throughput

0.464

High

458307

UGPB
sn-glycerol-3-phosphate-binding periplasmic protein UgpB

1

0

High-throughput

0.464

High

458309

DEGP
Periplasmic serine endoprotease DegP

1

0

High-throughput

0.464

High

458312

SECA
Protein translocase subunit SecA

1

0

High-throughput

0.464

High

458314

PARE
DNA topoisomerase 4 subunit B

1

0

High-throughput

0.464

High

458320

AGAI
Putative deaminase AgaI

1

0

High-throughput

0.464

High

458321

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.464

High

458323

RL5
Large ribosomal subunit protein uL5

1

0

High-throughput

0.464

High

458300

THIO
Thioredoxin 1

1

1

Small-scale

0.445

High

458311

EFTU2
Elongation factor Tu 2

1

2

High-throughput

0.445

High

458290

RS16
Small ribosomal subunit protein bS16

1

1

High-throughput

0.442

High

458291

RS2
Small ribosomal subunit protein uS2

1

1

High-throughput

0.442

High

340339

PTM3C
PTS system mannitol-specific EIICBA component

2

0

High-throughput

0.307

High

458324

YDIH
Uncharacterized protein YdiH

2

0

High-throughput

0.307

High

458292

RNH
Ribonuclease HI

1

0

High-throughput

0.279

Low

458294

TATE
Sec-independent protein translocase protein TatE

1

0

High-throughput

0.279

Low

458315

MUTL
DNA mismatch repair protein MutL

1

0

High-throughput

0.279

Low

458316

RHSE
Putative protein RhsE

1

0

High-throughput

0.279

Low

458319

YEHC
Probable fimbrial chaperone YehC

1

0

High-throughput

0.279

Low

458327

YAHN
Uncharacterized membrane protein YahN

1

0

High-throughput

0.279

Low

458328

GFCD
Uncharacterized lipoprotein GfcD

1

0

High-throughput

0.279

Low

458329

FLGA
Flagella basal body P-ring formation protein FlgA

1

0

High-throughput

0.279

Low

458330

RLUE
Ribosomal large subunit pseudouridine synthase E

1

0

High-throughput

0.279

Low

458287

RL29
Large ribosomal subunit protein uL29

1

0

High-throughput

0.253

Low

458331

YEGL
Uncharacterized protein YegL

1

0

High-throughput

0.253

Low

458332

DSBG
Thiol:disulfide interchange protein DsbG

1

0

High-throughput

0.253

Low


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Last updated: 15 Jul 2024