Protein: PRP11
Pre-mRNA-splicing factor PRP11

Gene: PRP11
Organism: Saccharomyces cerevisiae S288C
Interactions: 121
UniProt ID: Q07350

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

739280

PRP21
Pre-mRNA-splicing factor PRP21

14

4

Small-scale

0.982

High

1037759

CUS1
Cold sensitive U2 snRNA suppressor 1

5

1

High-throughput

0.922

High

1025658

NAM8
Protein NAM8

3

0

High-throughput

0.811

High

1059216

YRA1
RNA annealing protein YRA1

2

1

High-throughput

0.776

High

1059211

NCBP2
Nuclear cap-binding protein subunit 2

2

4

Small-scale

0.754

High

1059222

HSH49
Protein HSH49

2

1

High-throughput

0.754

High

625137

PRP9
Pre-mRNA-splicing factor PRP9

6

2

Small-scale

0.736

High

923754

CUS2
Cold sensitive U2 snRNA suppressor 2

1

2

Small-scale

0.713

High

817172

RSMB
Small nuclear ribonucleoprotein-associated protein B

5

2

High-throughput

0.712

High

1059212

RU2A
U2 small nuclear ribonucleoprotein A'

4

1

Small-scale

0.676

High

815247

IF4F1
Eukaryotic initiation factor 4F subunit p150

3

1

Small-scale

0.667

High

739211

PRP19
Pre-mRNA-processing factor 19

3

2

Small-scale

0.650

High

892792

SF3B1
U2 snRNP component HSH155

3

1

High-throughput

0.650

High

820846

RUXG
Small nuclear ribonucleoprotein G

3

3

High-throughput

0.643

High

746050

YME2
Mitochondrial escape protein 2

1

0

High-throughput

0.622

High

919583

YG5B
Uncharacterized RNA-binding protein YGR250C

1

1

High-throughput

0.618

High

1059214

CWC2
Pre-mRNA-splicing factor CWC2

1

4

High-throughput

0.618

High

1043511

CEF1
Pre-mRNA-splicing factor CEF1

2

2

High-throughput

0.611

High

672080

BUD31
Pre-mRNA-splicing factor BUD31

2

1

High-throughput

0.601

High

700157

PRP45
Pre-mRNA-processing protein 45

2

1

High-throughput

0.601

High

847838

SMD3
Small nuclear ribonucleoprotein Sm D3

2

5

High-throughput

0.601

High

1036183

SMD1
Small nuclear ribonucleoprotein Sm D1

2

1

High-throughput

0.601

High

1047389

RSE1
Pre-mRNA-splicing factor RSE1

2

1

High-throughput

0.601

High

1054386

SMD2
Small nuclear ribonucleoprotein Sm D2

2

1

High-throughput

0.601

High

1059219

PRP46
Pre-mRNA-splicing factor PRP46

2

3

High-throughput

0.601

High

797325

SP381
Pre-mRNA-splicing factor SPP381

2

0

High-throughput

0.595

High

628236

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

2

2

High-throughput

0.584

High

1059220

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

1

Small-scale

0.584

High

919225

SYF2
Pre-mRNA-splicing factor SYF2

2

0

High-throughput

0.576

High

1046716

SPC24
Kinetochore protein SPC24

2

0

High-throughput

0.570

High

1044065

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

2

0

Small-scale

0.561

High

815338

IF4F2
Eukaryotic initiation factor 4F subunit p130

2

2

Small-scale

0.552

High

893302

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

High-throughput

0.536

High

1039863

UTP17
NET1-associated nuclear protein 1

1

1

High-throughput

0.536

High

1044594

HMO1
High mobility group protein 1

1

2

High-throughput

0.515

High

722293

XPO1
Exportin-1

1

0

High-throughput

0.513

High

1043598

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.513

High

818062

LSM4
LSM complex subunit LSM4

1

3

High-throughput

0.508

High

925429

FAP1
FKBP12-associated protein 1

1

1

High-throughput

0.508

High

656892

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.501

High

676984

SRO9
RNA-binding protein SRO9

1

1

High-throughput

0.500

High

809423

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

863099

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.493

High

1042537

CWC21
Pre-mRNA-splicing factor CWC21

1

0

High-throughput

0.493

High

603557

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.489

High

836109

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.489

High

922127

COPA
Coatomer subunit alpha

1

1

High-throughput

0.489

High

1053119

UTP13
U3 small nucleolar RNA-associated protein 13

1

1

High-throughput

0.489

High

1055401

THI22
Thiamine biosynthesis protein THI22

1

2

High-throughput

0.489

High

780863

MUD2
Splicing factor MUD2

1

0

Small-scale

0.486

High

863248

IDS2
IME2-dependent-signaling protein

1

0

High-throughput

0.486

High

923209

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.486

High

1044780

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.486

High

1045171

SIZ1
E3 SUMO-protein ligase SIZ1

1

0

High-throughput

0.486

High

359073

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

0

High-throughput

0.479

High

408358

GAL1
Galactokinase

1

0

High-throughput

0.479

High

432368

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.479

High

439435

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.479

High

572654

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

578254

TAL1
Transaldolase

1

0

High-throughput

0.479

High

645547

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.479

High

680100

CDC48
Cell division control protein 48

1

0

High-throughput

0.479

High

724346

DHOM
Homoserine dehydrogenase

1

0

High-throughput

0.479

High

740228

RPN2
26S proteasome regulatory subunit RPN2

1

0

High-throughput

0.479

High

625052

PRP6
Pre-mRNA-splicing factor 6

1

5

High-throughput

0.479

High

638019

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

1

5

High-throughput

0.479

High

744174

BRR2
Pre-mRNA-splicing helicase BRR2

1

5

High-throughput

0.479

High

750312

PRP40
Pre-mRNA-processing protein PRP40

1

3

High-throughput

0.479

High

751798

PRP8
Pre-mRNA-splicing factor 8

1

1

High-throughput

0.479

High

757545

NCBP1
Nuclear cap-binding protein complex subunit 1

1

1

High-throughput

0.479

High

780231

SN114
Pre-mRNA-splicing factor SNU114

1

1

High-throughput

0.479

High

796469

SLT11
Pre-mRNA-splicing factor SLT11

1

1

High-throughput

0.479

High

829963

PRP17
Pre-mRNA-processing factor 17

1

3

High-throughput

0.479

High

933148

RUXF
Small nuclear ribonucleoprotein F

1

1

High-throughput

0.479

High

1044949

SYF1
Pre-mRNA-splicing factor SYF1

1

4

High-throughput

0.479

High

1057303

RDS3
Pre-mRNA-splicing factor RDS3

1

1

High-throughput

0.479

High

1059217

BBP
Branchpoint-bridging protein

1

1

High-throughput

0.479

High

1059218

CLF1
Pre-mRNA-splicing factor CLF1

1

5

High-throughput

0.479

High

597636

MER1
Meiotic recombination 1 protein

1

0

Small-scale

0.460

High

638088

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.458

High

702286

YJU2
Splicing factor YJU2

1

0

High-throughput

0.458

High

708318

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

781693

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

High-throughput

0.458

High

797696

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

919735

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.458

High

1044025

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

1053563

SN309
Pre-mRNA-splicing factor SNT309

1

0

High-throughput

0.458

High

1059215

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

367132

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.457

High

592526

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.457

High

626896

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.457

High

1059210

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

2

High-throughput

0.457

High

1059213

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

2

High-throughput

0.457

High

546456

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

742506

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

804499

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.445

High

945357

LSM3
LSM complex subunit LSM3

1

5

High-throughput

0.445

High

671170

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

793282

TAT1
Valine/tyrosine/tryptophan amino-acid permease 1

2

0

High-throughput

0.307

High

580144

HSC82
ATP-dependent molecular chaperone HSC82

2

0

High-throughput

0.305

High

808220

IPT1
Inositolphosphotransferase 1

1

0

High-throughput

0.282

High

446250

PHSG
Glycogen phosphorylase

1

0

High-throughput

0.279

Low

450746

KAD2
Adenylate kinase

1

0

High-throughput

0.279

Low

790232

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.279

Low

921485

SSK2
MAP kinase kinase kinase SSK2

1

0

High-throughput

0.279

Low

933120

ORN
Oligoribonuclease, mitochondrial

1

0

High-throughput

0.279

Low

638934

CBP3
Protein CBP3, mitochondrial

1

0

High-throughput

0.265

Low

780434

RT22
Ribosome assembly protein RSM22, mitochondrial

1

0

High-throughput

0.265

Low

818083

TMN3
Transmembrane 9 superfamily member 3

1

0

High-throughput

0.265

Low

1044283

YD131
F-box protein YDR131C

1

0

High-throughput

0.265

Low

1059221

EMC6
ER membrane protein complex subunit 6

1

0

High-throughput

0.265

Low

367817

ENO1
Enolase 1

1

0

High-throughput

0.261

Low

368762

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

394939

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.261

Low

555159

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

599081

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.261

Low

619387

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.261

Low

644847

CLH
Clathrin heavy chain

1

0

High-throughput

0.261

Low

760627

TSA1
Peroxiredoxin TSA1

1

0

High-throughput

0.261

Low

815754

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.261

Low

856572

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025