Interactor 1: SPY2 (O43597)
Protein sprouty homolog 2 (Spry-2)
Gene: SPRY2

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.748

The method score is based on:

Property Details
Experiments 32296183, 10940627, 17255109, 16893902, 17974561, 15004239, 16339969
Identification Methods two hybrid, pull down, affinity chromatography technology, unspecified method, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, filter binding
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008543 - fibroblast growth factor receptor signaling pathway
GO:0019901 - protein kinase binding
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 315
Hs

1 217
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Last updated: 15 Jul 2024