Protein: PLXB1
Plexin-B1 (Semaphorin receptor SEP)

Gene: PLXB1, PLXNB1
Organism: Homo sapiens
Interactions: 41
UniProt ID: O43157

Gene Ontology (top 5):
GO:0002116 - semaphorin receptor complex
GO:0004888 - transmembrane signaling receptor activity
GO:0005096 - GTPase activator activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

208132

RND1
Rho-related GTP-binding protein Rho6

5

20

Small-scale

0.931

High

208122

RND3
Rho-related GTP-binding protein RhoE

4

20

Small-scale

0.890

High

208119

RND2
Rho-related GTP-binding protein RhoN

3

20

Small-scale

0.853

High

208112

MET
Hepatocyte growth factor receptor

3

19

Small-scale

0.847

High

208134

SEM4D
Semaphorin-4D

2

20

Small-scale

0.802

High

208107

PLXB1
Plexin-B1

2

19

Small-scale

0.757

High

177348

ARHGB
Rho guanine nucleotide exchange factor 11

5

19

Small-scale

0.712

High

208127

RON
Macrophage-stimulating protein receptor

1

19

Small-scale

0.665

High

208138

SEM4A
Semaphorin-4A

1

20

Small-scale

0.647

High

208124

HBB
Hemoglobin subunit beta

2

2

High-throughput

0.628

High

208125

HBA
Hemoglobin subunit alpha

2

2

High-throughput

0.628

High

164185

NRP1
Neuropilin-1

1

20

Small-scale

0.621

High

208109

NRP2
Neuropilin-2

1

20

Small-scale

0.621

High

208141

PLXA1
Plexin-A1

1

19

Small-scale

0.621

High

126379

RHOD
Rho-related GTP-binding protein RhoD

1

20

Small-scale

0.618

High

208111

RASH
GTPase HRas

1

17

High-throughput

0.618

High

208121

RHOA
Transforming protein RhoA

1

20

Small-scale

0.618

High

208123

GRB2
Growth factor receptor-bound protein 2

2

19

Small-scale

0.608

High

165117

RASM
Ras-related protein M-Ras

1

11

Small-scale

0.575

High

208139

ARHGC
Rho guanine nucleotide exchange factor 12

1

15

Small-scale

0.552

High

208110

DIAP1
Protein diaphanous homolog 1

1

2

High-throughput

0.536

High

208133

GGH
Gamma-glutamyl hydrolase

1

5

High-throughput

0.536

High

208129

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

0

High-throughput

0.513

High

208131

CENPU
Centromere protein U

1

1

High-throughput

0.489

High

208135

ISG20
Interferon-stimulated gene 20 kDa protein

1

1

High-throughput

0.489

High

208136

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

3

High-throughput

0.489

High

208117

L1CAM
Neural cell adhesion molecule L1

1

8

Small-scale

0.481

High

208108

TGON2
Trans-Golgi network integral membrane protein 2

1

16

High-throughput

0.479

High

208113

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

6

Small-scale

0.479

High

208114

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

6

Small-scale

0.479

High

208116

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.479

High

208118

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

208128

SOX4
Transcription factor SOX-4

1

2

Small-scale

0.439

High

104874

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

208115

CALX
Calnexin

1

12

High-throughput

0.437

High

208130

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

208140

SMPX
Small muscular protein

2

0

High-throughput

0.328

High

208120

CF298
Cilia- and flagella-associated protein 298

1

0

High-throughput

0.279

Low

208137

CENPO
Centromere protein O

1

0

High-throughput

0.279

Low

208126

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025