HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: DAB1 (O75553)
Disabled homolog 1
Gene: DAB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14517291
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 588
+	Mm
		223010 NCK2_MOUSE (1-380): 3.58e-98: 298: 96.05		DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50
+	Hs
		269120 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00
+	Mm
		956235 NCK1_MOUSE (1-379): 6.79e-91: 279: 68.24		DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50
+	Hs
		209098 NCK2_HUMAN (1-380): 6.88e-99: 300: 100.00		ANS1B_HUMAN (9-229): 2.08e-44: 171: 17.70
+	Hs
		557659 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98
+	Hs
		203208 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		SYNJ1_HUMAN (96-588): 2.76e-38: 153: 15.26
+	Mm
		763385 FYN_MOUSE (7-137): 2.1e-23: 103: 20.30		DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50
+	Mm
		403429 SRC_MOUSE (6-153): 5.44e-20: 93.3: 17.33		DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50
+	Hs
		782772 CSK_HUMAN (191-378): 3.44e-32: 127: 24.87		DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98
+	Hs
		655317 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98
+	Hs
		454823 FGR_HUMAN (7-155): 1.02e-23: 104: 18.54		DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98
+	Hs
		412132 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98
+	Hs
		655522 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		NUMBL_HUMAN (3-574): 6.05e-39: 153: 12.50
+	Hs
		655498 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		DP13A_HUMAN (12-230): 3.59e-35: 143: 11.45
+	Hs
		655429 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		SHC3_HUMAN (10-354): 2.24e-35: 142: 16.53
+	Hs
		129347 P85B_HUMAN (21-380): 7.78e-23: 102: 13.10		DP13A_HUMAN (12-230): 3.59e-35: 143: 11.45
+	Hs
		253524 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		CAPON_HUMAN (11-325): 9.83e-36: 142: 14.37
+	Mm
		643078 P85A_MOUSE (166-379): 4.24e-24: 106: 16.36		SHC1_MOUSE (26-329): 2.11e-33: 136: 13.24
+	Mm
		403440 SRC_MOUSE (6-153): 5.44e-20: 93.3: 17.33		SHC3_MOUSE (10-351): 7.05e-37: 145: 16.06
+	Mm
		403430 SRC_MOUSE (6-153): 5.44e-20: 93.3: 17.33		SHC1_MOUSE (26-329): 2.11e-33: 136: 13.24