HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: SEM6A (Q9H2E6)
Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1)
Gene: SEMA6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 1030
+	Hs
		557792 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		SEM6A_HUMAN (1-1030): 0: 1031: 100.00
+	Hs
		1329264 ITSN2_HUMAN (3-309): 6.32e-28: 117: 18.31		SEM6A_HUMAN (1-1030): 0: 1031: 100.00
+	Hs
		259519 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		SEM7A_HUMAN (65-618): 1.83e-142: 443: 26.82
+	Hs
		195974 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		PLXB1_HUMAN (45-949): 1.68e-156: 512: 16.80
+	Hs
		259518 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		SEM7A_HUMAN (65-618): 1.83e-142: 443: 26.82
+	Hs
		259523 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		SEM7A_HUMAN (65-618): 1.83e-142: 443: 26.82