HitPredict

Interactor 1: PLRG1 (O43660)
Pleiotropic regulator 1
Gene: PLRG1

Interactor 2: SF3A2 (Q15428)
Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62)
Gene: SF3A2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 17332742
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0016607 - nuclear speck and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 514 Hs			1 464
+	Hs
		1073711 SNR40_HUMAN (26-356): 1.15e-62: 210: 17.51		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Sc
		991159 PRP46_YEAST (146-439): 1.87e-55: 193: 20.59		PRP11_YEAST (16-220): 7.74e-39: 143: 25.60
+	Hs
		302275 WDR5_HUMAN (20-315): 8.55e-56: 191: 13.06		SC31A_HUMAN (172-463): 1.67e-21: 100: 15.33
+	Hs
		903374 WDR5_HUMAN (20-315): 8.55e-56: 191: 13.06		KMT2C_HUMAN (73-462): 1.38e-16: 85.1: 12.59
+	Hs
		1264784 SNR40_HUMAN (26-356): 1.15e-62: 210: 17.51		TITIN_HUMAN (290-460): 7.67e-09: 60.4: 18.50
+	Mm
		903669 WDR5_MOUSE (20-315): 8.55e-56: 191: 13.06		KMT2C_MOUSE (89-446): 1e-12: 72.8: 11.73
+	Dm
		113977 GBLP_DROME (318-500): 7.62e-35: 134: 21.65		M9PB30_DROME (248-463): 5.32e-09: 61.2: 19.74