HitPredict

Interactor 1: SERA (O43175)
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37)
Gene: PHGDH

Interactor 2: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	22990118
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 533 Hs			1 2089
+	Hs
		1103168 CTBP1_HUMAN (21-384): 1.27e-117: 355: 29.89		MDC1_HUMAN (1-2089): 0: 680: 100.00
+	Hs
		209500 SERA_HUMAN (1-533): 0: 667: 100.00		BRCA1_HUMAN (405-2081): 8.49e-75: 279: 8.23
+	Hs
		209629 SERA_HUMAN (1-533): 0: 667: 100.00		TITIN_HUMAN (137-816): 5.64e-12: 74.2: 7.90
+	Hs
		799071 CTBP1_HUMAN (21-384): 1.27e-117: 355: 29.89		BRCA1_HUMAN (405-2081): 8.49e-75: 279: 8.23
+	Hs
		96935 CTBP1_HUMAN (21-384): 1.27e-117: 355: 29.89		E9PGC8_HUMAN (111-1784): 4.28e-70: 265: 9.68
+	Hs
		854032 CTBP1_HUMAN (21-384): 1.27e-117: 355: 29.89		KI67_HUMAN (38-1926): 1.25e-69: 263: 9.54
+	Hs
		1103451 CTBP1_HUMAN (21-384): 1.27e-117: 355: 29.89		SRRM2_HUMAN (97-1940): 1.48e-24: 115: 8.27
+	Hs
		1103484 CTBP1_HUMAN (21-384): 1.27e-117: 355: 29.89		PCLO_HUMAN (108-1946): 4.33e-21: 104: 7.82
+	Hs
		1103334 CTBP1_HUMAN (21-384): 1.27e-117: 355: 29.89		MINT_HUMAN (224-1896): 3.16e-16: 88.1: 11.94
+	Hs
		875650 CTBP1_HUMAN (21-384): 1.27e-117: 355: 29.89		PRC2A_HUMAN (609-1919): 1.32e-13: 79.2: 9.07