HitPredict

Interactor 1: BUB1 (O43683)
Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)
Gene: BUB1

Interactor 2: BUB1 (O43683)
Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)
Gene: BUB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 20360068
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Mad3_BUB1_I~Mad3_BUB1_I, Pkinase~Pkinase
Common GO terms GO:0000776 - kinetochore
GO:0000940 - outer kinetochore
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
and 16 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1085
Hs

1 1085
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Mm
+ Hs
+ Sp
+ Hs
+ Hs
+ Dm
+ Sp
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024