HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 1362
+	Hs
		244767 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00
+	Hs
		244210 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00
+	Sc
		767631 GLE2_YEAST (5-326): 1.95e-94: 286: 34.22		GCN5_YEAST (140-462): 1.42e-41: 161: 16.37
+	Sc
		715340 GLE2_YEAST (5-326): 1.95e-94: 286: 34.22		SPT7_YEAST (223-610): 3.64e-27: 122: 12.08
+	Hs
		943875 RAE1L_HUMAN (3-326): 2.75e-99: 299: 33.63		KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15
+	Dm
		113998 Q9W1T0_DROME (2-315): 6.17e-99: 296: 26.32		M9PB30_DROME (168-975): 2.55e-17: 90.9: 12.03
+	Hs
		631541 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43
+	Hs
		211219 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30
+	Hs
		631433 TAF5_HUMAN (65-295): 2.05e-24: 105: 18.35		BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43
+	Hs
		1066968 TAF5_HUMAN (65-295): 2.05e-24: 105: 18.35		BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53
+	Sp
		252179 NLE1_SCHPO (225-327): 1.32e-19: 91.2: 11.54		YK82_SCHPO (49-215): 1.43e-35: 147: 26.35
+	Hs
		1074790 TAF5_HUMAN (65-295): 2.05e-24: 105: 18.35		BRDT_HUMAN (26-339): 2.9e-26: 119: 19.24
+	Hs
		1074799 TAF5_HUMAN (65-295): 2.05e-24: 105: 18.35		PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30
+	Mm
		903669 WDR5_MOUSE (209-320): 6.93e-20: 90.4: 16.07		KMT2C_MOUSE (495-1183): 4.41e-22: 106: 13.55
+	Hs
		903409 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92
+	Dm
		1358857 WDS_DROME (222-320): 3.76e-18: 85.8: 17.17		Q9VTZ1_DROME (336-457): 5.41e-22: 105: 30.89
+	Hs
		903408 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15
+	Hs
		267784 TAF5L_HUMAN (17-146): 4.7e-09: 59.3: 36.23		KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92
+	Hs
		267783 TAF5L_HUMAN (17-146): 4.7e-09: 59.3: 36.23		KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15