HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 229
+	Sc
		477160 BUB3_YEAST (7-298): 2.45e-77: 241: 29.78		UBI4P_YEAST (1-228): 5.66e-90: 271: 96.05
+	Hs
		475614 RAE1L_HUMAN (3-326): 2.75e-99: 299: 33.63		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Hs
		476151 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Rn
		925834 LIS1_RAT (168-319): 3.02e-31: 123: 14.47		UBC_RAT (1-181): 2.6e-61: 206: 96.13
+	Rn
		921810 GNB5_RAT (13-206): 1.83e-26: 108: 21.57		UBC_RAT (1-181): 2.6e-61: 206: 96.13
+	Hs
		476181 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	At
		1091956 GPLPB_ARATH (65-295): 4.02e-21: 94: 17.92		UBQ3_ARATH (1-153): 2.79e-55: 180: 95.43
+	Hs
		475563 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	At
		187391 O22826_ARATH (207-327): 4.41e-16: 79.7: 14.75		UBQ3_ARATH (1-153): 2.79e-55: 180: 95.43
+	At
		1092188 GPLPC_ARATH (91-295): 1.39e-11: 66.2: 14.35		UBQ3_ARATH (1-153): 2.79e-55: 180: 95.43
+	Hs
		903105 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00
+	Hs
		397828 LIS1_HUMAN (168-319): 3.74e-31: 122: 14.47		ISG15_HUMAN (3-154): 1.46e-26: 102: 32.26