Protein: YLAT2
Y+L amino acid transporter 2 (Cationic amino acid transporter, y+ system) (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2)

Gene: YLAT2, SLC7A6
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q92536

Gene Ontology (top 5):
GO:0003333 - amino acid transmembrane transport
GO:0005886 - plasma membrane
GO:0006809 - nitric oxide biosynthetic process
GO:0015171 - amino acid transmembrane transporter activity
GO:0015174 - basic amino acid transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

467564

4F2
Amino acid transporter heavy chain SLC3A2

3

11

Small-scale

0.839

High

1363790

SCN3B
Sodium channel regulatory subunit beta-3

1

6

High-throughput

0.691

High

406915

MAS
Proto-oncogene Mas

2

17

High-throughput

0.628

High

1031828

LAT1
Large neutral amino acids transporter small subunit 1

1

16

High-throughput

0.575

High

1363793

YLAT1
Y+L amino acid transporter 1

1

15

High-throughput

0.575

High

1363795

DOLK
Dolichol kinase

2

1

High-throughput

0.553

High

135969

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

4

High-throughput

0.536

High

182697

GP182
G-protein coupled receptor 182

1

16

High-throughput

0.536

High

349510

TSN15
Tetraspanin-15

1

8

High-throughput

0.536

High

640438

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

15

High-throughput

0.536

High

733029

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

9

High-throughput

0.536

High

761276

RYK
Tyrosine-protein kinase RYK

1

12

High-throughput

0.536

High

833846

P2RY2
P2Y purinoceptor 2

1

12

High-throughput

0.536

High

835344

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

10

High-throughput

0.536

High

854560

S15A1
Solute carrier family 15 member 1

1

4

High-throughput

0.536

High

1053042

VMAT2
Synaptic vesicular amine transporter

1

7

High-throughput

0.536

High

1251669

T184A
Transmembrane protein 184A

1

1

High-throughput

0.536

High

1363781

EXOC4
Exocyst complex component 4

1

1

High-throughput

0.536

High

1363785

S22A4
Solute carrier family 22 member 4

1

5

High-throughput

0.536

High

1363796

LZTS1
Leucine zipper putative tumor suppressor 1

1

1

High-throughput

0.536

High

1363797

GPR45
Probable G-protein coupled receptor 45

1

10

High-throughput

0.536

High

50644

HACL2
2-hydroxyacyl-CoA lyase 2

1

6

High-throughput

0.489

High

163814

TCRG1
Transcription elongation regulator 1

1

1

High-throughput

0.489

High

283122

PSIP1
PC4 and SFRS1-interacting protein

1

1

High-throughput

0.489

High

451424

NFM
Neurofilament medium polypeptide

1

2

High-throughput

0.489

High

908430

HDGF
Hepatoma-derived growth factor

1

1

High-throughput

0.489

High

1206948

CEP78
Centrosomal protein of 78 kDa

1

2

High-throughput

0.489

High

1335879

RN169
E3 ubiquitin-protein ligase RNF169

1

1

High-throughput

0.489

High

1363788

SG196
Protein O-mannose kinase

1

2

High-throughput

0.489

High

1363794

CC14A
Dual specificity protein phosphatase CDC14A

1

2

High-throughput

0.489

High

126724

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

375786

RASK
GTPase KRas

1

20

High-throughput

0.479

High

431861

ITB1
Integrin beta-1

1

2

Small-scale

0.479

High

955431

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

962330

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

975155

ARF6
ADP-ribosylation factor 6

1

8

High-throughput

0.479

High

978201

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

988570

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

1015639

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

1363787

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1363789

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

250126

ADCY9
Adenylate cyclase type 9

1

3

High-throughput

0.445

High

261236

NSMA
Sphingomyelin phosphodiesterase 2

1

1

High-throughput

0.445

High

516437

CALM2
Calmodulin-2

1

2

High-throughput

0.445

High

548568

MPRI
Cation-independent mannose-6-phosphate receptor

1

4

High-throughput

0.445

High

564844

NCAM1
Neural cell adhesion molecule 1

1

2

High-throughput

0.445

High

648300

ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

1

4

High-throughput

0.445

High

1228764

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

3

High-throughput

0.445

High

1363784

SGPP1
Sphingosine-1-phosphate phosphatase 1

1

2

High-throughput

0.445

High

831145

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

956426

RAB2A
Ras-related protein Rab-2A

1

17

High-throughput

0.437

High

1270757

DDX46
Probable ATP-dependent RNA helicase DDX46

1

1

High-throughput

0.437

High

343858

SEM4F
Semaphorin-4F

1

0

High-throughput

0.426

High

1363792

GDE1
Glycerophosphodiester phosphodiesterase 1

1

0

High-throughput

0.426

High

2875

A0A0C4DG89
Probable ATP-dependent RNA helicase DDX46

1

1

High-throughput

0.407

High

139106

FAAH1
Fatty-acid amide hydrolase 1

1

1

High-throughput

0.407

High

144464

SCD
Stearoyl-CoA desaturase

1

2

High-throughput

0.407

High

1091959

SEC20
Vesicle transport protein SEC20

1

1

High-throughput

0.407

High

1288638

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

5

High-throughput

0.407

High

1334244

ATAD1
Outer mitochondrial transmembrane helix translocase

1

2

High-throughput

0.407

High

1336778

SIA7C
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

1

3

High-throughput

0.407

High

1358322

SCFD1
Sec1 family domain-containing protein 1

1

9

High-throughput

0.407

High

1363776

SNX19
Sorting nexin-19

1

5

High-throughput

0.407

High

1363778

GPI8
GPI-anchor transamidase

1

1

High-throughput

0.407

High

1363779

ESR2
Estrogen receptor beta

1

5

High-throughput

0.407

High

1363786

SNX25
Sorting nexin-25

1

5

High-throughput

0.407

High

487587

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.279

Low

1148309

CNN3
Calponin-3

1

0

High-throughput

0.279

Low

1231272

BLT3A
Bridge-like lipid transfer protein family member 3A

1

0

High-throughput

0.279

Low

1232765

CPIN1
Anamorsin

1

0

High-throughput

0.279

Low

1363777

ZN592
Zinc finger protein 592

1

0

High-throughput

0.279

Low

1363783

T22D3
TSC22 domain family protein 3

1

0

High-throughput

0.279

Low

1363791

APC11
Anaphase-promoting complex subunit 11

1

0

High-throughput

0.279

Low

1141519

OXA1L
Mitochondrial inner membrane protein OXA1L

1

0

High-throughput

0.232

Low

1363780

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.232

Low

1363782

F210B
Protein FAM210B, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025