HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26496610, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 328 Hs			1 539
+	At
		1105260 RAE1_ARATH (3-324): 5.63e-97: 292: 38.32		TCPD_ARATH (5-539): 0: 555: 64.43
+	Hs
		211135 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		211236 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		TCPH_HUMAN (12-538): 0: 549: 32.34
+	At
		138355 RAE1_ARATH (3-324): 5.63e-97: 292: 38.32		TCPE_ARATH (13-538): 0: 540: 33.71
+	Hs
		211133 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		843411 NLE1_HUMAN (86-326): 2.9e-49: 172: 13.10		TCPD_HUMAN (1-539): 0: 602: 100.00
+	Hs
		843299 POC1B_HUMAN (134-327): 7.29e-41: 150: 13.93		TCPD_HUMAN (1-539): 0: 602: 100.00
+	Hs
		826807 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		1306704 NLE1_HUMAN (86-326): 2.9e-49: 172: 13.10		TCPH_HUMAN (12-538): 0: 549: 32.34
+	Hs
		821437 NLE1_HUMAN (86-326): 2.9e-49: 172: 13.10		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		826784 POC1B_HUMAN (134-327): 7.29e-41: 150: 13.93		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		843139 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		TCPD_HUMAN (1-539): 0: 602: 100.00
+	Hs
		821326 POC1B_HUMAN (134-327): 7.29e-41: 150: 13.93		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		792942 LIS1_HUMAN (168-319): 3.74e-31: 122: 14.47		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		154662 GNB5_HUMAN (13-206): 2.53e-26: 109: 22.06		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		154696 GNB5_HUMAN (13-206): 2.53e-26: 109: 22.06		TCPH_HUMAN (12-538): 0: 549: 32.34
+	Hs
		154661 GNB5_HUMAN (13-206): 2.53e-26: 109: 22.06		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		826601 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		TCPG_HUMAN (12-537): 0: 553: 33.40
+	Hs
		821355 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		TCPE_HUMAN (13-535): 0: 540: 37.88
+	Hs
		821152 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		TCPE_HUMAN (13-535): 0: 540: 37.88