Protein: CTR3
Cationic amino acid transporter 3 (CAT-3) (CAT3) (Cationic amino acid transporter y+) (Solute carrier family 7 member 3)

Gene: CTR3, SLC7A3
Organism: Homo sapiens
Interactions: 142
UniProt ID: Q8WY07

Gene Ontology (top 5):
GO:0000064 - L-ornithine transmembrane transporter activity
GO:0005886 - plasma membrane
GO:0006865 - amino acid transport
GO:0015171 - amino acid transmembrane transporter activity
GO:0015189 - L-lysine transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1361326

PD1L1
Programmed cell death 1 ligand 1

2

12

High-throughput

0.789

High

142145

NPT3
Sodium-dependent phosphate transport protein 3

2

5

High-throughput

0.628

High

652220

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

2

8

High-throughput

0.628

High

1361328

CLC2D
C-type lectin domain family 2 member D

2

9

High-throughput

0.628

High

1361331

RXLT1
Ribitol-5-phosphate xylosyltransferase 1

2

1

High-throughput

0.628

High

851078

LPAR6
Lysophosphatidic acid receptor 6

2

12

High-throughput

0.611

High

1134137

NTCP
Hepatic sodium/bile acid cotransporter

2

2

High-throughput

0.606

High

1361290

TM237
Transmembrane protein 237

2

1

High-throughput

0.606

High

219340

B4GA1
Beta-1,4-glucuronyltransferase 1

3

1

High-throughput

0.604

High

760482

SDC2
Syndecan-2

2

0

High-throughput

0.602

High

1361304

CADM1
Cell adhesion molecule 1

1

2

High-throughput

0.575

High

1163594

RTN1
Reticulon-1

2

5

High-throughput

0.574

High

1361291

SEC62
Translocation protein SEC62

2

3

High-throughput

0.549

High

210415

MTLR
Motilin receptor

1

4

High-throughput

0.536

High

221467

OX2R
Orexin receptor type 2

1

2

High-throughput

0.536

High

260784

RAMP2
Receptor activity-modifying protein 2

1

1

High-throughput

0.536

High

619872

VCAM1
Vascular cell adhesion protein 1

1

3

High-throughput

0.536

High

640240

EPHA1
Ephrin type-A receptor 1

1

7

High-throughput

0.536

High

640436

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

14

High-throughput

0.536

High

641896

DRD4
D(4) dopamine receptor

1

3

High-throughput

0.536

High

867656

GPR12
G-protein coupled receptor 12

1

4

High-throughput

0.536

High

880180

PTH2R
Parathyroid hormone 2 receptor

1

10

High-throughput

0.536

High

1090104

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

9

High-throughput

0.536

High

1098927

KLRD1
Natural killer cells antigen CD94

1

9

High-throughput

0.536

High

1249503

VSTM1
V-set and transmembrane domain-containing protein 1

1

1

High-throughput

0.536

High

1316738

AGRG2
Adhesion G-protein coupled receptor G2

1

5

High-throughput

0.536

High

1339945

OR4N2
Olfactory receptor 4N2

1

3

High-throughput

0.536

High

1361282

AQP3
Aquaporin-3

1

1

High-throughput

0.536

High

1361283

LPAR1
Lysophosphatidic acid receptor 1

1

5

High-throughput

0.536

High

1361289

OPALI
Opalin

1

2

High-throughput

0.536

High

1361301

HCAR1
Hydroxycarboxylic acid receptor 1

1

11

High-throughput

0.536

High

1361308

S22A4
Solute carrier family 22 member 4

1

4

High-throughput

0.536

High

1361309

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

190561

COPT2
Protein SLC31A2

1

0

High-throughput

0.513

High

583939

KCNE1
Potassium voltage-gated channel subfamily E member 1

1

0

High-throughput

0.513

High

1361303

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.513

High

1361307

GPR88
G protein-coupled receptor 88

1

0

High-throughput

0.513

High

1361318

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

0

High-throughput

0.513

High

1361325

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.513

High

71233

HIDE1
Protein HIDE1

1

1

High-throughput

0.489

High

230716

NKG2F
NKG2-F type II integral membrane protein

1

3

High-throughput

0.489

High

253873

TPST2
Protein-tyrosine sulfotransferase 2

1

6

High-throughput

0.489

High

698951

CALX
Calnexin

1

4

High-throughput

0.489

High

926815

VMAT1
Chromaffin granule amine transporter

1

9

High-throughput

0.489

High

1361284

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

2

High-throughput

0.489

High

1361293

DNJC2
DnaJ homolog subfamily C member 2

1

4

High-throughput

0.489

High

1361310

AT133
Polyamine-transporting ATPase 13A3

1

5

High-throughput

0.489

High

171535

S27A2
Long-chain fatty acid transport protein 2

1

1

High-throughput

0.445

High

184204

RER1
Protein RER1

1

1

High-throughput

0.445

High

333121

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

3

High-throughput

0.445

High

410966

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

14

High-throughput

0.445

High

439803

INSR
Insulin receptor

1

14

High-throughput

0.445

High

465589

IGF1R
Insulin-like growth factor 1 receptor

1

11

High-throughput

0.445

High

548564

MPRI
Cation-independent mannose-6-phosphate receptor

1

4

High-throughput

0.445

High

602251

TMM11
Transmembrane protein 11, mitochondrial

1

1

High-throughput

0.445

High

648298

ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

1

4

High-throughput

0.445

High

813177

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

1

High-throughput

0.445

High

857514

NOTC1
Neurogenic locus notch homolog protein 1

1

6

High-throughput

0.445

High

890760

PSN2
Presenilin-2

1

2

High-throughput

0.445

High

1047669

NOTC2
Neurogenic locus notch homolog protein 2

1

4

High-throughput

0.445

High

1089990

LMAN2
Vesicular integral-membrane protein VIP36

1

3

High-throughput

0.445

High

1101763

PTK7
Inactive tyrosine-protein kinase 7

1

4

High-throughput

0.445

High

1122637

MLEC
Malectin

1

1

High-throughput

0.445

High

1147395

EPHA7
Ephrin type-A receptor 7

1

8

High-throughput

0.445

High

1159777

OCLN
Occludin

1

2

High-throughput

0.445

High

1219678

TM268
Transmembrane protein 268

1

1

High-throughput

0.445

High

1253781

QSOX2
Sulfhydryl oxidase 2

1

3

High-throughput

0.445

High

1326200

PNKD
Probable thioesterase PNKD

1

1

High-throughput

0.445

High

1340215

MSPD2
Motile sperm domain-containing protein 2

1

4

High-throughput

0.445

High

1361292

SORT
Sortilin

1

1

High-throughput

0.445

High

1361294

CHP1
Calcineurin B homologous protein 1

1

4

High-throughput

0.445

High

1361298

TMM43
Transmembrane protein 43

1

4

High-throughput

0.445

High

1361300

SGPP1
Sphingosine-1-phosphate phosphatase 1

1

2

High-throughput

0.445

High

1361306

YIPF3
Protein YIPF3

1

3

High-throughput

0.445

High

1361313

GBA2
Non-lysosomal glucosylceramidase

1

2

High-throughput

0.445

High

1361316

WDR6
tRNA

1

1

High-throughput

0.445

High

1361317

ABCB6
ATP-binding cassette sub-family B member 6

1

4

High-throughput

0.445

High

1361322

T106B
Transmembrane protein 106B

1

1

High-throughput

0.445

High

1361323

ANO10
Anoctamin-10

1

1

High-throughput

0.445

High

1361329

NB5R1
NADH-cytochrome b5 reductase 1

1

8

High-throughput

0.445

High

1361334

NPTN
Neuroplastin

1

9

High-throughput

0.445

High

764922

CTNB1
Catenin beta-1

1

0

High-throughput

0.426

High

1086062

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.426

High

50643

HACL2
2-hydroxyacyl-CoA lyase 2

1

6

High-throughput

0.407

High

85383

GPHRA
Golgi pH regulator A

1

6

High-throughput

0.407

High

160908

STX16
Syntaxin-16

1

10

High-throughput

0.407

High

161234

EI24
Etoposide-induced protein 2.4 homolog

1

1

High-throughput

0.407

High

163574

TPP1
Tripeptidyl-peptidase 1

1

1

High-throughput

0.407

High

178971

SCAM2
Secretory carrier-associated membrane protein 2

1

7

High-throughput

0.407

High

186434

TM9S1
Transmembrane 9 superfamily member 1

1

7

High-throughput

0.407

High

270035

XYLK
Glycosaminoglycan xylosylkinase

1

2

High-throughput

0.407

High

280286

SC22B
Vesicle-trafficking protein SEC22b

1

3

High-throughput

0.407

High

316540

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

5

High-throughput

0.407

High

318034

TOM70
Mitochondrial import receptor subunit TOM70

1

4

High-throughput

0.407

High

327384

ZFPL1
Zinc finger protein-like 1

1

3

High-throughput

0.407

High

341456

CDS2
Phosphatidate cytidylyltransferase 2

1

1

High-throughput

0.407

High

417633

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

3

High-throughput

0.407

High

418312

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

3

High-throughput

0.407

High

469153

SRPRA
Signal recognition particle receptor subunit alpha

1

4

High-throughput

0.407

High

536278

PPAL
Lysosomal acid phosphatase

1

2

High-throughput

0.407

High

596693

NCPR
NADPH--cytochrome P450 reductase

1

4

High-throughput

0.407

High

693413

CERS1
Ceramide synthase 1

1

8

High-throughput

0.407

High

847426

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

3

High-throughput

0.407

High

1016725

MXRA7
Matrix-remodeling-associated protein 7

1

1

High-throughput

0.407

High

1147813

DHC24
Delta(24)-sterol reductase

1

3

High-throughput

0.407

High

1150602

TRAM1
Translocating chain-associated membrane protein 1

1

8

High-throughput

0.407

High

1203073

TM41B
Transmembrane protein 41B

1

3

High-throughput

0.407

High

1205009

RABL3
Rab-like protein 3

1

14

High-throughput

0.407

High

1273257

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

4

High-throughput

0.407

High

1278046

MAVS
Mitochondrial antiviral-signaling protein

1

3

High-throughput

0.407

High

1281257

TMED4
Transmembrane emp24 domain-containing protein 4

1

9

High-throughput

0.407

High

1286496

SCD5
Stearoyl-CoA desaturase 5

1

2

High-throughput

0.407

High

1334242

ATAD1
Outer mitochondrial transmembrane helix translocase

1

2

High-throughput

0.407

High

1336992

DIK2A
Divergent protein kinase domain 2A

1

2

High-throughput

0.407

High

1352473

GPX8
Probable glutathione peroxidase 8

1

1

High-throughput

0.407

High

1358320

SCFD1
Sec1 family domain-containing protein 1

1

9

High-throughput

0.407

High

1361285

YIPF6
Protein YIPF6

1

6

High-throughput

0.407

High

1361286

CREL1
Protein disulfide isomerase CRELD1

1

3

High-throughput

0.407

High

1361295

SGMR1
Sigma non-opioid intracellular receptor 1

1

4

High-throughput

0.407

High

1361296

PGAP4
GPI-N-acetylgalactosamine transferase PGAP4

1

3

High-throughput

0.407

High

1361297

ALG1
Chitobiosyldiphosphodolichol beta-mannosyltransferase

1

2

High-throughput

0.407

High

1361302

B2L13
Bcl-2-like protein 13

1

1

High-throughput

0.407

High

1361305

LNP
Endoplasmic reticulum junction formation protein lunapark

1

3

High-throughput

0.407

High

1361312

FKRP
Ribitol 5-phosphate transferase FKRP

1

2

High-throughput

0.407

High

1361314

SEC12
Guanine nucleotide-exchange factor SEC12

1

5

High-throughput

0.407

High

1361315

TM9S3
Transmembrane 9 superfamily member 3

1

7

High-throughput

0.407

High

1361319

VPS45
Vacuolar protein sorting-associated protein 45

1

9

High-throughput

0.407

High

1361320

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

8

High-throughput

0.407

High

1361321

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

3

High-throughput

0.407

High

1361327

CNIH4
Protein cornichon homolog 4

1

1

High-throughput

0.407

High

1361330

TMCO1
Calcium load-activated calcium channel

1

3

High-throughput

0.407

High

1361332

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

2

High-throughput

0.407

High

1361288

WDFY2
WD repeat and FYVE domain-containing protein 2

4

0

High-throughput

0.360

High

1361287

TXD15
Thioredoxin domain-containing protein 15

3

0

High-throughput

0.347

High

1361311

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.328

High

254299

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

1

0

High-throughput

0.232

Low

281627

MTX2
Metaxin-2

1

0

High-throughput

0.232

Low

547661

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.232

Low

1164489

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.232

Low

1361299

TM109
Voltage-gated monoatomic cation channel TMEM109

1

0

High-throughput

0.232

Low

1361324

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.232

Low

1361333

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025