HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	15388328
Identification Methods	affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 482
+	Hs
		211222 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		1270358 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		1270370 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		903202 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		903404 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		177249 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Dm
		1182201 EBI_DROME (1-86): 1.34e-17: 85.4: 18.39		Q7KTS4_DROME (7-435): 0: 564: 56.52
+	Dm
		1279322 EBI_DROME (1-86): 1.34e-17: 85.4: 18.39		Q9VNC2_DROME (7-435): 0: 560: 56.29
+	Hs
		211269 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		1260173 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		HDAC7_HUMAN (10-410): 1.09e-137: 421: 21.56