Protein: TMM43
Transmembrane protein 43 (Protein LUMA)

Gene: TMM43, TMEM43
Organism: Homo sapiens
Interactions: 202
UniProt ID: Q9BTV4

Gene Ontology (top 5):
GO:0005637 - nuclear inner membrane
GO:0005788 - endoplasmic reticulum lumen
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1413700

RTN4
Reticulon-4

3

1

High-throughput

0.667

High

1163606

RTN1
Reticulon-1

2

1

High-throughput

0.628

High

951390

SC61B
Protein transport protein Sec61 subunit beta

3

0

High-throughput

0.628

High

1242912

S39A4
Zinc transporter ZIP4

3

0

High-throughput

0.622

High

901531

RAB7A
Ras-related protein Rab-7a

2

1

High-throughput

0.611

High

1413706

VAPA
Vesicle-associated membrane protein-associated protein A

2

1

High-throughput

0.611

High

1246212

APOA5
Apolipoprotein A-V

2

1

High-throughput

0.606

High

1413716

5MP1
eIF5-mimic protein 1

3

1

High-throughput

0.604

High

1350050

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.602

High

1413694

YIPF3
Protein YIPF3

2

0

High-throughput

0.602

High

1200251

T4S20
Transmembrane 4 L6 family member 20

2

0

High-throughput

0.585

High

1413696

TOR3A
Torsin-3A

2

0

High-throughput

0.585

High

387746

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

2

0

High-throughput

0.580

High

1125631

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

2

0

High-throughput

0.580

High

1207600

F209A
Protein FAM209A

2

0

High-throughput

0.580

High

1327948

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

0

High-throughput

0.580

High

1413698

SYNG1
Synapse differentiation-inducing gene protein 1

2

0

High-throughput

0.580

High

1413715

PCY1B
Choline-phosphate cytidylyltransferase B

2

0

High-throughput

0.580

High

322056

ENDD1
Endonuclease domain-containing 1 protein

2

0

High-throughput

0.576

High

564309

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.576

High

1271305

5MP2
eIF5-mimic protein 2

2

1

High-throughput

0.558

High

425616

ISG15
Ubiquitin-like protein ISG15

2

0

Small-scale

0.547

High

1143092

KPCD1
Serine/threonine-protein kinase D1

2

0

High-throughput

0.547

High

477462

CD63
CD63 antigen

1

2

High-throughput

0.536

High

538672

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

3

High-throughput

0.536

High

618418

TSN8
Tetraspanin-8

1

2

High-throughput

0.536

High

1382050

T106A
Transmembrane protein 106A

1

1

High-throughput

0.536

High

1393439

REEP6
Receptor expression-enhancing protein 6

1

1

High-throughput

0.536

High

789954

FDFT
Squalene synthase

1

0

High-throughput

0.518

High

387319

APOA1
Apolipoprotein A-I

1

1

High-throughput

0.515

High

141861

ACKR2
Atypical chemokine receptor 2

1

0

High-throughput

0.513

High

167174

T4S5
Transmembrane 4 L6 family member 5

1

0

High-throughput

0.513

High

297259

PRAF3
PRA1 family protein 3

1

0

High-throughput

0.513

High

417713

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.513

High

418397

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.513

High

483199

CLCA
Clathrin light chain A

1

0

High-throughput

0.513

High

505195

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.513

High

506901

CFC1
Cryptic protein

1

0

High-throughput

0.513

High

530307

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

548106

PSPC
Surfactant protein C

1

0

High-throughput

0.513

High

699054

CALX
Calnexin

1

0

High-throughput

0.513

High

813199

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.513

High

890047

PSN1
Presenilin-1

1

0

High-throughput

0.513

High

895020

EMD
Emerin

1

0

Small-scale

0.513

High

905768

CAV2
Caveolin-2

1

0

High-throughput

0.513

High

963595

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.513

High

976523

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.513

High

1013533

COG7
Conserved oligomeric Golgi complex subunit 7

1

0

High-throughput

0.513

High

1055352

APLP2
Amyloid beta precursor like protein 2

1

0

High-throughput

0.513

High

1142164

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.513

High

1315121

EXOC8
Exocyst complex component 8

1

0

High-throughput

0.513

High

1326889

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.513

High

1333695

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.513

High

1413690

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

1413695

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

1413699

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

1413707

DNJB9
DnaJ homolog subfamily B member 9

1

0

High-throughput

0.513

High

843931

HD
Huntingtin

1

0

High-throughput

0.493

High

1027162

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.489

High

333164

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

Small-scale

0.479

High

412532

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

967348

TSN5
Tetraspanin-5

1

2

High-throughput

0.479

High

1287425

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

High-throughput

0.479

High

1334536

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

1384812

OTUL
Ubiquitin thioesterase otulin

1

1

Small-scale

0.479

High

1413692

RNF26
E3 ubiquitin-protein ligase RNF26

1

1

High-throughput

0.479

High

1413697

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1413703

T106B
Transmembrane protein 106B

1

1

High-throughput

0.479

High

1413711

ALK
ALK tyrosine kinase receptor

1

1

Small-scale

0.479

High

218703

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

242767

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

253106

PLIN3
Perilipin-3

1

0

High-throughput

0.458

High

258329

TRI13
E3 ubiquitin-protein ligase TRIM13

1

0

High-throughput

0.458

High

320022

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

353891

BCL10
B-cell lymphoma/leukemia 10

1

0

Small-scale

0.458

High

363797

EGFR
Epidermal growth factor receptor

1

0

Small-scale

0.458

High

566821

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.458

High

582616

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.458

High

944370

NAC3
Sodium/calcium exchanger 3

1

0

High-throughput

0.458

High

947269

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

1136340

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.458

High

1136680

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.458

High

1161634

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1163410

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

1164079

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

0

High-throughput

0.458

High

1178348

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1203081

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.458

High

1205481

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.458

High

1253235

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

0

High-throughput

0.458

High

1312593

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

1330375

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

1351960

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.458

High

1383041

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1393646

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1413687

TMM43
Transmembrane protein 43

1

0

Small-scale

0.458

High

1413709

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

211173

CTR4
Cationic amino acid transporter 4

1

4

High-throughput

0.445

High

256131

S19A2
Thiamine transporter 1

1

1

High-throughput

0.445

High

303280

S22A5
Organic cation/carnitine transporter 2

1

2

High-throughput

0.445

High

337134

NPT2B
Sodium-dependent phosphate transport protein 2B

1

1

High-throughput

0.445

High

652244

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

3

High-throughput

0.445

High

722599

CTR1
High affinity cationic amino acid transporter 1

1

4

High-throughput

0.445

High

912710

CTR2
Cationic amino acid transporter 2

1

4

High-throughput

0.445

High

1007412

S35A1
CMP-sialic acid transporter

1

1

High-throughput

0.445

High

1007451

S35B1
Solute carrier family 35 member B1

1

2

High-throughput

0.445

High

1055415

NPT2A
Sodium-dependent phosphate transport protein 2A

1

1

High-throughput

0.445

High

1131605

MFS10
Major facilitator superfamily domain-containing protein 10

1

2

High-throughput

0.445

High

1199090

CTL4
Choline transporter-like protein 4

1

2

High-throughput

0.445

High

1246108

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

3

High-throughput

0.445

High

1309762

CTL2
Choline transporter-like protein 2

1

2

High-throughput

0.445

High

1348047

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

3

High-throughput

0.445

High

1348630

S7A14
Solute carrier family 7 member 14

1

4

High-throughput

0.445

High

1359493

CTL1
Choline transporter-like protein 1

1

2

High-throughput

0.445

High

1361298

CTR3
Cationic amino acid transporter 3

1

4

High-throughput

0.445

High

1381024

S35B4
Nucleotide sugar transporter SLC35B4

1

3

High-throughput

0.445

High

1413693

S19A3
Thiamine transporter 2

1

1

High-throughput

0.445

High

1413701

S35C2
Solute carrier family 35 member C2

1

1

High-throughput

0.445

High

1413713

S35A3
UDP-N-acetylglucosamine transporter

1

1

High-throughput

0.445

High

1137998

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.437

High

1238798

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1307914

ARMC8
Armadillo repeat-containing protein 8

1

1

High-throughput

0.437

High

1392448

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

1413704

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

178378

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.426

High

336275

BRI3
Membrane protein BRI3

1

0

High-throughput

0.426

High

351246

MOT3
Monocarboxylate transporter 3

1

0

High-throughput

0.426

High

690362

STOM
Stomatin

1

0

High-throughput

0.426

High

827907

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.426

High

870301

S6A12
Sodium- and chloride-dependent betaine transporter

1

0

High-throughput

0.426

High

880868

NRAM2
Natural resistance-associated macrophage protein 2

1

0

High-throughput

0.426

High

1157196

S15A2
Solute carrier family 15 member 2

1

0

High-throughput

0.426

High

1175894

TM241
UDP-N-acetylglucosamine transporter TMEM241

1

0

High-throughput

0.426

High

1180311

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.426

High

1236296

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1240947

S27A4
Long-chain fatty acid transport protein 4

1

0

High-throughput

0.426

High

1280809

S35E3
Solute carrier family 35 member E3

1

0

High-throughput

0.426

High

1337932

ZNT7
Zinc transporter 7

1

0

High-throughput

0.426

High

1352102

S26A7
Anion exchange transporter

1

0

High-throughput

0.426

High

1389478

NTCP4
Sodium/bile acid cotransporter 4

1

0

High-throughput

0.426

High

1413708

SUN2
SUN domain-containing protein 2

1

0

Small-scale

0.426

High

1413717

S4A7
Sodium bicarbonate cotransporter 3

1

0

High-throughput

0.426

High

1211954

S35F1
Solute carrier family 35 member F1

1

4

High-throughput

0.407

High

1234932

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.407

High

1308956

S22A9
Organic anion transporter 7

1

2

High-throughput

0.407

High

1312977

S35F2
Solute carrier family 35 member F2

1

2

High-throughput

0.407

High

1326975

SVOP
Synaptic vesicle 2-related protein

1

2

High-throughput

0.407

High

1115395

CUL4B
Cullin-4B

4

0

Small-scale

0.360

High

1393245

GRM2B
GRAM domain-containing protein 2B

3

0

High-throughput

0.348

High

1307779

SIAH1
E3 ubiquitin-protein ligase SIAH1

2

0

High-throughput

0.341

High

547955

UTER
Uteroglobin

2

0

High-throughput

0.316

High

1187547

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

1244030

ZCH12
Zinc finger CCHC domain-containing protein 12

2

0

High-throughput

0.316

High

1413710

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

2

0

High-throughput

0.316

High

1389575

SAAL1
Protein SAAL1

2

0

High-throughput

0.313

High

898793

RL14
Large ribosomal subunit protein eL14

2

0

High-throughput

0.305

High

1413689

CAR10
Caspase recruitment domain-containing protein 10

1

0

Small-scale

0.292

High

273711

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

0

High-throughput

0.279

Low

288282

SPAG6
Sperm-associated antigen 6

1

0

High-throughput

0.279

Low

1025895

FANCC
Fanconi anemia group C protein

1

0

High-throughput

0.279

Low

1066013

VAC14
Protein VAC14 homolog

1

0

High-throughput

0.279

Low

1329473

KTAP2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

1

0

High-throughput

0.279

Low

1361355

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

1369056

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.279

Low

1380044

CAVN3
Caveolae-associated protein 3

1

0

High-throughput

0.279

Low

1381693

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.279

Low

1386345

FAF2
FAS-associated factor 2

1

0

High-throughput

0.279

Low

1387676

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

1388175

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.279

Low

1413688

TM109
Voltage-gated monoatomic cation channel TMEM109

1

0

High-throughput

0.279

Low

1413705

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.279

Low

1413714

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

1327409

TT39C
Tetratricopeptide repeat protein 39C

1

0

High-throughput

0.269

Low

1413712

NALDL
Aminopeptidase NAALADL1

1

0

High-throughput

0.269

Low

386168

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

294264

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

589562

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696369

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769040

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

831339

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

905091

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.249

Low

965203

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

971005

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1005037

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1107156

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

1140776

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

1156844

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

1162523

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1229659

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1252209

SYNE3
Nesprin-3

1

0

High-throughput

0.249

Low

1255313

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1288576

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.249

Low

1367153

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1380644

FBX32
F-box only protein 32

1

0

High-throughput

0.249

Low

1386948

GASP2
G-protein coupled receptor-associated sorting protein 2

1

0

High-throughput

0.249

Low

1403563

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.249

Low

1413691

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.249

Low

1413702

ANLN
Anillin

1

0

High-throughput

0.249

Low

1103353

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.232

Low

1242211

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.232

Low

1313986

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.232

Low

1333420

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025