HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 538
+	Dr
		1193337 Q7ZTX2_DANRE (127-325): 5.38e-47: 163: 15.35		Q7ZUU9_DANRE (1-506): 1.49e-116: 355: 89.02
+	Hs
		211260 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		NLE1_HUMAN (2-135): 8.57e-34: 135: 18.38
+	Hs
		943844 RAE1L_HUMAN (3-326): 2.75e-99: 299: 33.63		SMU1_HUMAN (179-320): 3.28e-21: 99: 13.79
+	Hs
		943879 RAE1L_HUMAN (3-326): 2.75e-99: 299: 33.63		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Ca
		483033 TUP1_CANAL (1-206): 8.77e-55: 188: 17.18		TUP1_CANAL (100-402): 3.81e-53: 190: 16.10
+	Hs
		211219 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		PHIP_HUMAN (227-374): 6.69e-15: 80.4: 13.91
+	Hs
		211150 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		1240442 POC1B_HUMAN (134-327): 7.29e-41: 150: 13.93		POC1A_HUMAN (145-538): 3.26e-45: 165: 10.89
+	Mm
		925836 LIS1_MOUSE (168-319): 3.02e-31: 123: 14.47		LIS1_MOUSE (104-423): 6.46e-53: 186: 9.65
+	Hs
		792935 LIS1_HUMAN (168-319): 3.74e-31: 122: 14.47		LIS1_HUMAN (104-423): 9.57e-53: 186: 9.65
+	Hs
		1346954 NLE1_HUMAN (86-326): 2.9e-49: 172: 13.10		NLE1_HUMAN (2-135): 8.57e-34: 135: 18.38
+	Sp
		999842 TUP11_SCHPO (1-213): 6.22e-64: 214: 17.90		TUP12_SCHPO (226-339): 4.64e-10: 64.3: 18.33
+	Sp
		999838 TUP11_SCHPO (1-213): 6.22e-64: 214: 17.90		TUP11_SCHPO (2-58): 7.11e-09: 60.4: 14.04
+	Hs
		1103007 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		SMU1_HUMAN (179-320): 3.28e-21: 99: 13.79
+	Hs
		1281292 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		903551 NLE1_HUMAN (86-326): 2.9e-49: 172: 13.10		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		903418 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		1074799 TAF5_HUMAN (65-295): 2.05e-24: 105: 18.35		PHIP_HUMAN (227-374): 6.69e-15: 80.4: 13.91
+	Hs
		792949 LIS1_HUMAN (168-319): 3.74e-31: 122: 14.47		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41