Protein: FIG4
Polyphosphoinositide phosphatase (EC 3.1.3.-) (EC 3.1.3.36) (EC 3.1.3.86) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3) (Serine-protein phosphatase FIG4) (EC 3.1.3.16)

Gene: FIG4
Organism: Homo sapiens
Interactions: 28
UniProt ID: Q92562

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0004439 - phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005811 - lipid droplet

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1065988

VAC14
Protein VAC14 homolog

6

1

Small-scale

0.735

High

1364782

FYV1
1-phosphatidylinositol 3-phosphate 5-kinase

5

4

Small-scale

0.712

High

242455

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.584

High

1364781

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.580

High

592950

ANK1
Ankyrin-1

2

1

High-throughput

0.574

High

1364779

SNX27
Sorting nexin-27

1

3

High-throughput

0.536

High

1364784

NPTN
Neuroplastin

1

1

High-throughput

0.536

High

1169022

CSPP1
Centrosome and spindle pole-associated protein 1

1

0

High-throughput

0.513

High

422751

A4
Amyloid-beta precursor protein

1

1

Small-scale

0.501

High

901443

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.479

High

1116270

PTC1
Protein patched homolog 1

1

1

Small-scale

0.479

High

1276253

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.479

High

1364778

MY18A
Unconventional myosin-XVIIIa

1

0

High-throughput

0.458

High

331195

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.437

High

1035816

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.437

High

1114968

CUL4A
Cullin-4A

1

1

High-throughput

0.437

High

1364783

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

1364780

SL9A7
Sodium/hydrogen exchanger 7

1

0

High-throughput

0.426

High

96867

E9PDH4
Phosphoinositide kinase, FYVE-type zinc finger containing

1

4

High-throughput

0.407

High

1010959

BAT1
b(0,+)-type amino acid transporter 1

1

3

High-throughput

0.407

High

340375

YETS4
YEATS domain-containing protein 4

1

0

High-throughput

0.279

Low

867311

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

1054624

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.279

Low

1144105

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.279

Low

904350

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.249

Low

1041685

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

0

Small-scale

0.249

Low

1185165

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

0

High-throughput

0.249

Low

1339544

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025