HitPredict

Interactor 1: TLX3 (O43711)
T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2)
Gene: TLX3

Interactor 2: TBL1R (Q9BZK7)
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)
Gene: TBL1XR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 291 Hs			1 514
+	Hs
		211773 TLX3_HUMAN (1-291): 5.64e-54: 179: 100.00		TBL1X_HUMAN (1-514): 1.2e-150: 444: 86.34
+	Hs
		245566 TLX1_HUMAN (2-290): 2.68e-37: 136: 54.30		TBL1X_HUMAN (1-514): 1.2e-150: 444: 86.34
+	Hs
		245638 NANOG_HUMAN (102-281): 1.1e-34: 129: 29.47		TBL1X_HUMAN (1-514): 1.2e-150: 444: 86.34
+	Hs
		245559 PAX7_HUMAN (9-282): 6.05e-32: 125: 15.77		TBL1X_HUMAN (1-514): 1.2e-150: 444: 86.34
+	Hs
		213284 TLX2_HUMAN (11-290): 4.67e-32: 121: 58.87		TBL1X_HUMAN (1-514): 1.2e-150: 444: 86.34
+	Hs
		245644 VSX1_HUMAN (6-243): 6.02e-30: 117: 20.17		TBL1X_HUMAN (1-514): 1.2e-150: 444: 86.34
+	Hs
		211820 TLX3_HUMAN (1-291): 5.64e-54: 179: 100.00		WDR5_HUMAN (17-334): 1.51e-56: 193: 14.46
+	Hs
		211866 TLX3_HUMAN (1-291): 5.64e-54: 179: 100.00		SMU1_HUMAN (329-513): 4.3e-39: 150: 19.00
+	Hs
		620138 PAX7_HUMAN (9-282): 6.05e-32: 125: 15.77		WDR5_HUMAN (17-334): 1.51e-56: 193: 14.46
+	Hs
		282819 HXA5_HUMAN (17-241): 9.17e-32: 120: 19.49		CIAO1_HUMAN (169-472): 3.95e-22: 99.4: 27.94