HitPredict

Interactor 1: HTSF1 (O43719)
17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1) (Tat-SF1)
Gene: HTATSF1

Interactor 2: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28242625
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035861 - site of double-strand break
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 755 Hs			1 143
+	Hs
		474005 PAB4L_HUMAN (116-346): 2.02e-51: 185: 20.17		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		555437 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		516349 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		555478 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		470365 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47
+	Hs
		391555 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70
+	Hs
		470273 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47
+	Hs
		391681 PABP4_HUMAN (62-285): 4.99e-31: 131: 12.66		H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70
+	Hs
		641916 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60
+	Hs
		470244 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47
+	Sc
		376566 PABP_YEAST (62-422): 9.79e-26: 114: 13.46		H2A2_YEAST (16-124): 4.61e-53: 165: 82.57