HitPredict

Interactor 1: HTSF1 (O43719)
17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1) (Tat-SF1)
Gene: HTATSF1

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24999758
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 755 Hs			1 656
+	Hs
		212166 HTSF1_HUMAN (1-755): 2.64e-92: 306: 100.00		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		641874 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		1031411 PABP4_HUMAN (62-285): 4.99e-31: 131: 12.66		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		516620 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		642763 ELAV4_HUMAN (88-420): 8.56e-36: 141: 13.20		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		1077435 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		641727 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		680441 TIA1_HUMAN (127-364): 1.82e-31: 129: 16.12		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		967202 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Mm
		857328 TIA1_MOUSE (127-376): 1.76e-31: 129: 15.75		EWS_MOUSE (1-656): 4.67e-42: 163: 94.06
+	Dm
		1098207 U2AF2_DROME (129-356): 5.43e-34: 137: 20.85		CAZ_DROME (236-550): 2.31e-36: 142: 37.11
+	Hs
		967116 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		726795 PABP4_HUMAN (62-285): 4.99e-31: 131: 12.66		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		516383 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Sc
		376785 PABP_YEAST (62-422): 9.79e-26: 114: 13.46		HRB1_YEAST (241-452): 4.75e-35: 140: 21.76
+	Hs
		726846 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		318605 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02
+	Hs
		726756 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Sc
		376649 PABP_YEAST (62-422): 9.79e-26: 114: 13.46		GBP2_YEAST (343-453): 3.82e-16: 83.2: 24.56
+	Hs
		409731 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		CO5A2_HUMAN (3-351): 4.52e-09: 62.1: 9.80