Interactor 1: SPOP (O43791)
Speckle-type POZ protein (HIB homolog 1) (Roadkill homolog 1)
Gene: SPOP

Interactor 2: SPOP (O43791)
Speckle-type POZ protein (HIB homolog 1) (Roadkill homolog 1)
Gene: SPOP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 25278611, 27220849, 22632832, 31559706, 30244836, 32905556, 33894201, 34133717, 36856266, 15240113
Identification Methods affinity chromatography technology, pull down, enzymatic study, molecular sieving, cosedimentation in solution, electron microscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BTB~BTB, MATH~MATH
Common GO terms GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0016607 - nuclear speck
and 6 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 374
Hs

1 374
+ Mm
+ Hs
+ Hs
+ Dm
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Ce
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024