HitPredict

Interactor 1: CPSF5 (O43809)
Cleavage and polyadenylation specificity factor subunit 5 (Cleavage and polyadenylation specificity factor 25 kDa subunit) (CPSF 25 kDa subunit) (Cleavage factor Im complex 25 kDa subunit) (CFIm25) (Nucleoside diphosphate-linked moiety X motif 21) (Nudix motif 21) (Nudix hydrolase 21) (Pre-mRNA cleavage factor Im 68 kDa subunit)
Gene: NUDT21

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	38280479, 38223760
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 227 Hs			1 504
+	Hs
		125027 CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		215016 CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		215043 CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		214877 CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Hs
		215033 CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		215050 CPSF5_HUMAN (1-227): 4.65e-152: 423: 100.00		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61
+	Dm
		1115152 Q9VSY2_DROME (7-184): 6.33e-106: 305: 73.55		YAP1_DROME (52-268): 1.16e-44: 163: 29.25