Protein: ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (M2 antigen complex 70 kDa subunit) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2)

Gene: ODP2, DLAT
Organism: Homo sapiens
Interactions: 200
UniProt ID: P10515

Gene Ontology (top 5):
GO:0004742 - dihydrolipoyllysine-residue acetyltransferase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006006 - glucose metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

489688

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

5

8

Small-scale

0.929

High

452588

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

3

12

High-throughput

0.861

High

126213

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

2

13

Small-scale

0.767

High

489685

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

2

13

Small-scale

0.715

High

489749

PDK3
[Pyruvate dehydrogenase

4

9

Small-scale

0.698

High

489708

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

12

High-throughput

0.691

High

440310

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

11

High-throughput

0.618

High

489748

PDK2
[Pyruvate dehydrogenase

2

9

Small-scale

0.602

High

489747

PDK1
[Pyruvate dehydrogenase

2

9

Small-scale

0.595

High

489844

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

5

High-throughput

0.586

High

345777

MYC
Myc proto-oncogene protein

3

3

Small-scale

0.585

High

262683

CISY
Citrate synthase, mitochondrial

2

2

High-throughput

0.584

High

489721

PPT1
Palmitoyl-protein thioesterase 1

2

1

Small-scale

0.584

High

489712

STA5A
Signal transducer and activator of transcription 5A

2

3

High-throughput

0.574

High

489736

FOXD4
Forkhead box protein D4

2

1

High-throughput

0.574

High

489695

RAB5A
Ras-related protein Rab-5A

2

8

High-throughput

0.571

High

489782

ESR2
Estrogen receptor beta

2

7

High-throughput

0.571

High

489839

HECD1
E3 ubiquitin-protein ligase HECTD1

2

7

High-throughput

0.533

High

204964

TGON2
Trans-Golgi network integral membrane protein 2

2

1

High-throughput

0.521

High

489701

CALX
Calnexin

2

1

High-throughput

0.521

High

489760

ARHGG
Rho guanine nucleotide exchange factor 16

2

1

High-throughput

0.521

High

489765

PKHG7
Pleckstrin homology domain-containing family G member 7

2

2

High-throughput

0.521

High

489834

RHG23
Rho GTPase-activating protein 23

2

3

High-throughput

0.521

High

489826

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

1

5

High-throughput

0.501

High

296504

KPCD3
Serine/threonine-protein kinase D3

1

1

High-throughput

0.494

High

489724

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

1

High-throughput

0.494

High

489692

MIF
Macrophage migration inhibitory factor

1

1

High-throughput

0.489

High

489703

CLIP1
CAP-Gly domain-containing linker protein 1

1

6

High-throughput

0.489

High

489716

KI67
Proliferation marker protein Ki-67

1

3

High-throughput

0.489

High

489719

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.489

High

489723

STA5B
Signal transducer and activator of transcription 5B

1

3

High-throughput

0.489

High

489783

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.489

High

489836

HDAC6
Histone deacetylase 6

1

3

High-throughput

0.489

High

59094

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.479

High

63276

MET15
12S rRNA N4-methylcytidine

1

2

High-throughput

0.479

High

226342

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

241947

PAGE4
P antigen family member 4

1

1

High-throughput

0.479

High

264818

MPPB
Mitochondrial-processing peptidase subunit beta

1

9

High-throughput

0.479

High

269970

RF1M
Peptide chain release factor 1, mitochondrial

1

10

High-throughput

0.479

High

327340

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

4

High-throughput

0.479

High

336833

OTC
Ornithine transcarbamylase, mitochondrial

1

3

High-throughput

0.479

High

373584

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

377043

GCR
Glucocorticoid receptor

1

7

Small-scale

0.479

High

429807

CATL1
Procathepsin L

1

1

High-throughput

0.479

High

486445

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.479

High

489686

CH60
60 kDa heat shock protein, mitochondrial

1

5

High-throughput

0.479

High

489687

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

489689

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

2

High-throughput

0.479

High

489709

GRP75
Stress-70 protein, mitochondrial

1

9

High-throughput

0.479

High

489710

MDHM
Malate dehydrogenase, mitochondrial

1

4

High-throughput

0.479

High

489714

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

High-throughput

0.479

High

489715

EFTS
Elongation factor Ts, mitochondrial

1

3

High-throughput

0.479

High

489717

IF2M
Translation initiation factor IF-2, mitochondrial

1

9

High-throughput

0.479

High

489720

EFTU
Elongation factor Tu, mitochondrial

1

6

High-throughput

0.479

High

489731

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

2

High-throughput

0.479

High

489733

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

Small-scale

0.479

High

489735

MPPA
Mitochondrial-processing peptidase subunit alpha

1

9

High-throughput

0.479

High

489740

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

6

High-throughput

0.479

High

489741

ICT1
Large ribosomal subunit protein mL62

1

2

High-throughput

0.479

High

489745

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.479

High

489750

SURF1
Surfeit locus protein 1

1

1

High-throughput

0.479

High

489754

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

3

High-throughput

0.479

High

489757

SYAM
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

489763

MRM1
rRNA methyltransferase 1, mitochondrial

1

2

High-throughput

0.479

High

489764

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

6

High-throughput

0.479

High

489768

COX15
Heme A synthase COX15

1

1

High-throughput

0.479

High

489769

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

9

High-throughput

0.479

High

489773

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.479

High

489785

FAKD4
FAST kinase domain-containing protein 4

1

9

High-throughput

0.479

High

489786

MCUR1
Mitochondrial calcium uniporter regulator 1

1

3

High-throughput

0.479

High

489787

CHCH1
Small ribosomal subunit protein mS37

1

1

High-throughput

0.479

High

489789

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

6

High-throughput

0.479

High

489790

RRFM
Ribosome-recycling factor, mitochondrial

1

3

High-throughput

0.479

High

489793

EFGM
Elongation factor G, mitochondrial

1

8

High-throughput

0.479

High

489798

TACO1
Translational activator of cytochrome c oxidase 1

1

3

High-throughput

0.479

High

489800

MTG1
Mitochondrial ribosome-associated GTPase 1

1

2

High-throughput

0.479

High

489801

TR61B
tRNA

1

2

High-throughput

0.479

High

489802

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

3

High-throughput

0.479

High

489803

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.479

High

489806

RT26
Small ribosomal subunit protein mS26

1

3

High-throughput

0.479

High

489809

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

4

High-throughput

0.479

High

489811

IF3M
Translation initiation factor IF-3, mitochondrial

1

2

High-throughput

0.479

High

489813

MTRFR
Mitochondrial translation release factor in rescue

1

10

High-throughput

0.479

High

489815

MTG2
Mitochondrial ribosome-associated GTPase 2

1

6

High-throughput

0.479

High

489817

MET17
Ribosome assembly protein METTL17, mitochondrial

1

3

High-throughput

0.479

High

489818

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

3

High-throughput

0.479

High

489819

SFXN1
Sideroflexin-1

1

3

High-throughput

0.479

High

489822

NGRN
Neugrin

1

1

High-throughput

0.479

High

489827

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

2

High-throughput

0.479

High

489828

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

4

High-throughput

0.479

High

489829

AKIP
Small ribosomal subunit protein mS38

1

1

High-throughput

0.479

High

489833

MRES1
Mitochondrial transcription rescue factor 1

1

3

High-throughput

0.479

High

489837

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

10

High-throughput

0.479

High

489841

RM11
Large ribosomal subunit protein uL11m

1

3

High-throughput

0.479

High

489842

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

Small-scale

0.479

High

177799

TMPS2
Transmembrane protease serine 2

1

4

High-throughput

0.470

High

489780

CLC4D
C-type lectin domain family 4 member D

1

2

High-throughput

0.470

High

449505

HMGB1
High mobility group protein B1

1

5

Small-scale

0.464

High

455022

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

473367

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

489832

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

489838

KS6A6
Ribosomal protein S6 kinase alpha-6

1

0

High-throughput

0.458

High

489694

TAL1
T-cell acute lymphocytic leukemia protein 1

1

2

High-throughput

0.457

High

377894

PRIO
Major prion protein

1

1

High-throughput

0.445

High

489758

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

489808

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

3

High-throughput

0.445

High

489814

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

3

High-throughput

0.445

High

100418

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

119108

LEG9
Galectin-9

1

3

High-throughput

0.437

High

150829

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

2

High-throughput

0.437

High

172967

RT12
Small ribosomal subunit protein uS12m

1

1

High-throughput

0.437

High

241430

H2B1K
Histone H2B type 1-K

1

1

High-throughput

0.437

High

255458

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.437

High

294296

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.437

High

301570

TRI37
E3 ubiquitin-protein ligase TRIM37

1

4

High-throughput

0.437

High

325603

LATS1
Serine/threonine-protein kinase LATS1

1

4

High-throughput

0.437

High

328713

TOP3B
DNA topoisomerase 3-beta-1

1

3

High-throughput

0.437

High

378949

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.437

High

384154

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

489690

IFM1
Interferon-induced transmembrane protein 1

1

3

High-throughput

0.437

High

489691

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.437

High

489696

CBL
E3 ubiquitin-protein ligase CBL

1

2

High-throughput

0.437

High

489697

BRD2
Bromodomain-containing protein 2

1

7

High-throughput

0.437

High

489699

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.437

High

489700

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

489702

PML
Protein PML

1

3

High-throughput

0.437

High

489704

STIP1
Stress-induced-phosphoprotein 1

1

5

High-throughput

0.437

High

489706

MERL
Merlin

1

3

High-throughput

0.437

High

489707

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

489711

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

489718

YAP1
Transcriptional coactivator YAP1

1

4

Small-scale

0.437

High

489722

RAB9A
Ras-related protein Rab-9A

1

4

High-throughput

0.437

High

489725

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

489726

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.437

High

489728

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.437

High

489729

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.437

High

489732

UBE3A
Ubiquitin-protein ligase E3A

1

4

High-throughput

0.437

High

489734

QOR
Quinone oxidoreductase

1

4

High-throughput

0.437

High

489737

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

2

High-throughput

0.437

High

489738

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.437

High

489742

RBM39
RNA-binding protein 39

1

2

High-throughput

0.437

High

489746

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.437

High

489751

EZH2
Histone-lysine N-methyltransferase EZH2

1

7

High-throughput

0.437

High

489755

DJC21
DnaJ homolog subfamily C member 21

1

2

High-throughput

0.437

High

489759

SYDE2
Rho GTPase-activating protein SYDE2

1

3

High-throughput

0.437

High

489762

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

489766

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

489771

TM11B
Transmembrane protease serine 11B

1

4

High-throughput

0.437

High

489774

CUL9
Cullin-9

1

1

High-throughput

0.437

High

489776

RHG24
Rho GTPase-activating protein 24

1

2

High-throughput

0.437

High

489777

FBXW8
F-box/WD repeat-containing protein 8

1

3

High-throughput

0.437

High

489781

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.437

High

489784

H2B1H
Histone H2B type 1-H

1

1

High-throughput

0.437

High

489788

ARMC5
Armadillo repeat-containing protein 5

1

3

High-throughput

0.437

High

489796

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.437

High

489797

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

1

High-throughput

0.437

High

489799

CQ080
Mitochondrial nucleoid-associated protein 1

1

3

High-throughput

0.437

High

489807

RHG39
Rho GTPase-activating protein 39

1

2

High-throughput

0.437

High

489816

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

489821

DNJC4
DnaJ homolog subfamily C member 4

1

6

High-throughput

0.437

High

489823

TF7L2
Transcription factor 7-like 2

1

1

High-throughput

0.437

High

489824

ANLN
Anillin

1

2

High-throughput

0.437

High

489825

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.437

High

489830

DJC28
DnaJ homolog subfamily C member 28

1

1

High-throughput

0.437

High

489831

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.437

High

489835

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.437

High

489840

CLC4E
C-type lectin domain family 4 member E

1

2

High-throughput

0.437

High

489843

DJC15
DnaJ homolog subfamily C member 15

1

2

High-throughput

0.437

High

376140

ANXA1
Annexin A1

1

2

Small-scale

0.407

High

401305

JUN
Transcription factor Jun

1

3

High-throughput

0.407

High

489713

CNDD3
Condensin-2 complex subunit D3

1

3

High-throughput

0.407

High

489761

CP135
Centrosomal protein of 135 kDa

1

9

High-throughput

0.407

High

489767

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

3

High-throughput

0.407

High

489772

TLK2
Serine/threonine-protein kinase tousled-like 2

1

2

High-throughput

0.407

High

489775

CNTRB
Centrobin

1

5

High-throughput

0.407

High

489779

POC5
Centrosomal protein POC5

1

3

High-throughput

0.407

High

489794

SCN2A
Sodium channel protein type 2 subunit alpha

1

3

High-throughput

0.407

High

489804

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

3

High-throughput

0.407

High

489810

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

3

High-throughput

0.407

High

489791

DOCK6
Dedicator of cytokinesis protein 6

2

0

High-throughput

0.298

High

489739

CUL1
Cullin-1

1

0

High-throughput

0.279

Low

489770

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

428891

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.249

Low

489693

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

489698

PSA3
Proteasome subunit alpha type-3

1

0

Small-scale

0.249

Low

489705

HPPD
4-hydroxyphenylpyruvate dioxygenase

1

0

Small-scale

0.249

Low

489727

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.249

Low

489730

K1C17
Keratin, type I cytoskeletal 17

1

0

High-throughput

0.249

Low

489743

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

489744

PAF15
PCNA-associated factor

1

0

Small-scale

0.249

Low

489752

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.249

Low

489753

CDKN3
Cyclin-dependent kinase inhibitor 3

1

0

High-throughput

0.249

Low

489756

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

489778

UBR7
Putative E3 ubiquitin-protein ligase UBR7

1

0

High-throughput

0.249

Low

489792

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

489795

TS101
Tumor susceptibility gene 101 protein

1

0

Small-scale

0.249

Low

489805

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

489812

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

0

Small-scale

0.249

Low

489820

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024