HitPredict

Interactor 1: ORC5 (O43913)
Origin recognition complex subunit 5
Gene: ORC5

Interactor 2: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 12614612, 15232106
Identification Methods two hybrid, pull down, protein array
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MCM_lid~ORC5_C
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0003688 - DNA replication origin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 435
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024