Protein: ARK72
Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (AFB1 aldehyde reductase 1) (AFB1-AR 1) (Aldoketoreductase 7) (Succinic semialdehyde reductase) (SSA reductase)

Gene: ARK72, AKR7A2
Organism: Homo sapiens
Interactions: 70
UniProt ID: O43488

Gene Ontology (top 5):
GO:0004032 - aldose reductase (NADPH) activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

217237

ARK73
Aldo-keto reductase family 7 member A3

9

15

High-throughput

0.971

High

217233

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

14

High-throughput

0.698

High

217276

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

15

High-throughput

0.575

High

217235

KTNA1
Katanin p60 ATPase-containing subunit A1

1

7

High-throughput

0.536

High

217246

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.536

High

217251

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

2

High-throughput

0.536

High

217253

ACTY
Beta-centractin

1

3

High-throughput

0.536

High

217257

ACTZ
Alpha-centractin

1

3

High-throughput

0.536

High

217263

BIRC2
Baculoviral IAP repeat-containing protein 2

1

2

High-throughput

0.536

High

217291

ARP10
Actin-related protein 10

1

1

High-throughput

0.536

High

217298

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.536

High

133327

DCTN6
Dynactin subunit 6

1

0

High-throughput

0.513

High

217236

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.513

High

217245

RALA
Ras-related protein Ral-A

1

0

High-throughput

0.513

High

217248

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.513

High

217252

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.513

High

217254

MSH6
DNA mismatch repair protein Msh6

1

0

High-throughput

0.513

High

217256

CF298
Cilia- and flagella-associated protein 298

1

0

High-throughput

0.513

High

217261

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.513

High

217262

FADD
FAS-associated death domain protein

1

0

High-throughput

0.513

High

217265

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.513

High

217266

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.513

High

217267

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.513

High

217272

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

217283

MB12A
Multivesicular body subunit 12A

1

0

High-throughput

0.513

High

217287

VP37B
Vacuolar protein sorting-associated protein 37B

1

0

High-throughput

0.513

High

217294

DCTN4
Dynactin subunit 4

1

0

High-throughput

0.513

High

217296

FAN1
Fanconi-associated nuclease 1

1

0

High-throughput

0.513

High

217279

CYGB
Cytoglobin

1

0

Small-scale

0.504

High

217255

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

217281

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

217275

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

1

1

High-throughput

0.489

High

217282

TRI63
E3 ubiquitin-protein ligase TRIM63

1

6

Small-scale

0.481

High

169833

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

217234

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

217239

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.479

High

217240

FINC
Fibronectin

1

1

High-throughput

0.479

High

217242

INSR
Insulin receptor

1

2

High-throughput

0.479

High

217247

ITA4
Integrin alpha-4

1

1

High-throughput

0.479

High

217260

HSF1
Heat shock factor protein 1

1

3

High-throughput

0.479

High

217264

MTM1
Myotubularin

1

1

High-throughput

0.479

High

217268

PTN21
Tyrosine-protein phosphatase non-receptor type 21

1

1

High-throughput

0.479

High

217271

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

217280

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

217284

MTMRC
Myotubularin-related protein 12

1

1

High-throughput

0.479

High

217288

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

3

Small-scale

0.479

High

217292

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

217293

TBK1
Serine/threonine-protein kinase TBK1

1

6

High-throughput

0.479

High

217274

MCPH1
Microcephalin

1

0

Small-scale

0.460

High

124558

EYA2
Protein phosphatase EYA2

1

0

High-throughput

0.458

High

217241

GCR
Glucocorticoid receptor

1

0

High-throughput

0.458

High

217259

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

217273

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

0

High-throughput

0.458

High

217285

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

217286

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

217297

PTN22
Tyrosine-protein phosphatase non-receptor type 22

1

0

High-throughput

0.458

High

217289

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

217244

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

217249

VCAM1
Vascular cell adhesion protein 1

1

2

High-throughput

0.445

High

217269

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

217290

DDX28
Probable ATP-dependent RNA helicase DDX28

1

4

High-throughput

0.445

High

217277

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.438

High

217243

IGF1R
Insulin-like growth factor 1 receptor

1

2

High-throughput

0.437

High

217250

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

217258

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

0

High-throughput

0.426

High

217238

VENTX
Homeobox protein VENTX

1

2

High-throughput

0.407

High

217295

ZBTB1
Zinc finger and BTB domain-containing protein 1

3

0

High-throughput

0.339

High

217270

CTR9
RNA polymerase-associated protein CTR9 homolog

1

0

High-throughput

0.279

Low

217278

LEO1
RNA polymerase-associated protein LEO1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025