HitPredict

Interactor 1: ORC5 (O43913)
Origin recognition complex subunit 5
Gene: ORC5

Interactor 2: ORC1 (Q13415)
Origin recognition complex subunit 1 (Replication control protein 1)
Gene: ORC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 26496610, 12614612, 31160578, 15232106, 16549788, 22398447, 17716973
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, protein array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA_16, AAA_16~AAA_lid_10
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0000808 - origin recognition complex
GO:0003688 - DNA replication origin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 4 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 435
Hs

1 861
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024