Interactor 1: TYOBP (O43914)
TYRO protein tyrosine kinase-binding protein (DNAX-activation protein 12) (Killer-activating receptor-associated protein) (KAR-associated protein)
Gene: TYROBP

Interactor 2: TREM2 (Q9NZC2)
Triggering receptor expressed on myeloid cells 2 (TREM-2) (Triggering receptor expressed on monocytes 2)
Gene: TREM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 0.55 0.583

The method score is based on:

Property Details
Experiments 11602640, 28490631
Identification Methods anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, Split renilla luciferase complementation, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002282 - microglial cell activation involved in immune response
GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0010628 - positive regulation of gene expression
GO:0016020 - membrane
and 4 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024