HitPredict

Interactor 1: AIRE (O43918)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)
Gene: AIRE

Interactor 2: IPO7 (O95373)
Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7)
Gene: IPO7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20085707
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0042393 - histone binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 545 Hs			1 1038
+	Mm
		1322279 AIRE_MOUSE (16-544): 2.93e-123: 374: 71.72		IPO7_MOUSE (1-1038): 0: 902: 99.42
+	Hs
		312422 TRI33_HUMAN (336-540): 1.26e-16: 85.6: 16.13		IPO7_HUMAN (1-1038): 0: 902: 100.00
+	Hs
		217482 AIRE_HUMAN (1-545): 1.25e-134: 403: 100.00		IMB1_HUMAN (5-785): 2.49e-114: 375: 12.82
+	Mm
		936171 AIRE_MOUSE (16-544): 2.93e-123: 374: 71.72		IMB1_MOUSE (5-785): 2.08e-113: 373: 12.95
+	Hs
		874493 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		XPO2_HUMAN (2-921): 1.6e-168: 521: 17.50
+	Hs
		874613 TRI33_HUMAN (336-540): 1.26e-16: 85.6: 16.13		XPO2_HUMAN (2-921): 1.6e-168: 521: 17.50
+	Hs
		1060930 SP110_HUMAN (2-297): 4.05e-35: 142: 16.77		IMB1_HUMAN (5-785): 2.49e-114: 375: 12.82
+	Hs
		1273242 TRI33_HUMAN (336-540): 1.26e-16: 85.6: 16.13		TNPO1_HUMAN (12-892): 7.7e-134: 428: 13.08
+	Hs
		1018484 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		IMB1_HUMAN (5-785): 2.49e-114: 375: 12.82
+	Hs
		127402 TRI33_HUMAN (336-540): 1.26e-16: 85.6: 16.13		IPO5_HUMAN (4-955): 1.57e-121: 400: 11.44
+	Hs
		1299145 TRI33_HUMAN (336-540): 1.26e-16: 85.6: 16.13		IPO9_HUMAN (4-996): 5e-121: 398: 15.05