HitPredict

Interactor 1: AIRE (O43918)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)
Gene: AIRE

Interactor 2: S10A9 (P06702)
Protein S100-A9 (Calgranulin-B) (Calprotectin L1H subunit) (Leukocyte L1 complex heavy chain) (Migration inhibitory factor-related protein 14) (MRP-14) (p14) (S100 calcium-binding protein A9)
Gene: S100A9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008270 - zinc ion binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 545 Hs			1 114
+	Hs
		217449 AIRE_HUMAN (1-545): 1.25e-134: 403: 100.00		S10A7_HUMAN (6-105): 8.64e-26: 94.2: 24.75
+	Hs
		416427 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		S10A9_HUMAN (1-114): 4.07e-47: 148: 100.00
+	Hs
		416414 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		S10A9_HUMAN (1-114): 4.07e-47: 148: 100.00
+	Hs
		1059716 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		HORN_HUMAN (5-97): 3.47e-32: 120: 29.03
+	Hs
		639056 UHRF1_HUMAN (268-410): 2.94e-28: 121: 23.87		S100P_HUMAN (5-97): 2.82e-35: 118: 36.56
+	Hs
		1018566 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		HORN_HUMAN (5-97): 3.47e-32: 120: 29.03
+	Hs
		1059662 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		FILA2_HUMAN (5-106): 5.21e-28: 108: 30.91
+	Hs
		331697 NSD2_HUMAN (30-345): 3.09e-17: 87.5: 14.80		S10A9_HUMAN (1-114): 4.07e-47: 148: 100.00
+	Hs
		416542 TRI33_HUMAN (336-540): 1.26e-16: 85.6: 16.13		S10A9_HUMAN (1-114): 4.07e-47: 148: 100.00
+	Hs
		396737 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		S10A8_HUMAN (5-100): 3.01e-29: 102: 25.00
+	Hs
		991045 SP110_HUMAN (2-297): 4.05e-35: 142: 16.77		TRHY_HUMAN (5-97): 7.45e-20: 85: 23.66
+	Hs
		1018521 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		FILA2_HUMAN (5-106): 5.21e-28: 108: 30.91
+	Hs
		596279 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		FILA_HUMAN (5-107): 2e-23: 95.4: 34.62
+	Hs
		678449 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		S10A7_HUMAN (6-105): 8.64e-26: 94.2: 24.75
+	Hs
		396727 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		S10A8_HUMAN (5-100): 3.01e-29: 102: 25.00
+	Hs
		164496 TRI66_HUMAN (400-540): 1.72e-19: 94.8: 20.41		CRNN_HUMAN (5-108): 1.1e-33: 123: 25.96
+	Hs
		642984 PHF12_HUMAN (295-340): 4.7e-09: 61.2: 54.17		S10A4_HUMAN (7-101): 5.27e-33: 112: 29.47