HitPredict

Interactor 1: AIRE (O43918)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)
Gene: AIRE

Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20953165
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 545 Hs			1 136
+	Hs
		217467 AIRE_HUMAN (1-545): 1.25e-134: 403: 100.00		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Mm
		935466 AIRE_MOUSE (16-544): 2.93e-123: 374: 71.72		H31_MOUSE (1-136): 6.88e-62: 187: 97.06
+	Hs
		299045 PHF14_HUMAN (126-484): 3.61e-44: 169: 16.71		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		299049 PHF14_HUMAN (126-484): 3.61e-44: 169: 16.71		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		617322 SP100_HUMAN (3-296): 1.81e-36: 146: 13.81		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		934879 JADE1_HUMAN (120-523): 6.93e-35: 141: 12.28		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1152679 JADE1_HUMAN (120-523): 6.93e-35: 141: 12.28		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		1086265 PF21A_HUMAN (130-352): 7.15e-33: 135: 23.38		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		952529 PF21A_HUMAN (130-352): 7.15e-33: 135: 23.38		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		1174623 PF21A_HUMAN (130-352): 7.15e-33: 135: 23.38		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		934770 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1059646 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Mm
		56901 CHD5_MOUSE (92-496): 2.13e-30: 128: 14.91		H33_MOUSE (1-136): 4.53e-61: 185: 93.38
+	Hs
		952343 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		1059689 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		299041 PHF14_HUMAN (126-484): 3.61e-44: 169: 16.71		CENPA_HUMAN (9-133): 3.54e-44: 142: 49.24
+	Sc
		902057 RCO1_YEAST (143-476): 9.27e-35: 140: 14.89		H3_YEAST (1-136): 1.43e-55: 171: 86.03
+	Hs
		935016 CHD5_HUMAN (288-504): 6.06e-28: 121: 17.41		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1086233 CHD5_HUMAN (288-504): 6.06e-28: 121: 17.41		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		1059677 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		H3C_HUMAN (1-136): 2.16e-58: 178: 90.44