HitPredict

Interactor 1: PDE6D (O43924)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta) (Protein p17)
Gene: PDE6D

Interactor 2: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	36662618, 23698361
Identification Methods	affinity chromatography technology, amplified luminescent proximity homogeneous assay
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 150 Hs			1 189
+	Hs
		217693 PDE6D_HUMAN (1-150): 1.96e-98: 281: 100.00		RASH_HUMAN (1-188): 6.53e-87: 255: 86.77
+	Hs
		217712 PDE6D_HUMAN (1-150): 1.96e-98: 281: 100.00		RAB13_HUMAN (4-186): 7.7e-72: 217: 36.76
+	Hs
		217719 PDE6D_HUMAN (1-150): 1.96e-98: 281: 100.00		RAP1A_HUMAN (1-165): 7.83e-63: 194: 58.08