HitPredict

Interactor 1: KGB1 (O44408)
GLH-binding kinase 1 (EC 2.7.11.24)
Gene: kgb-1

Interactor 2: GLH1 (P34689)
ATP-dependent RNA helicase glh-1 (EC 3.6.4.13) (Germline helicase 1)
Gene: glh-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	17699606, 12435362
Identification Methods	enzymatic study, two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0017151 - DEAD/H-box RNA helicase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 390 Ce			1 763
+	Ce
		136900 KGB1_CAEEL (1-390): 7.51e-140: 405: 100.00		GLH3_CAEEL (53-763): 1.47e-151: 460: 54.56
+	Rn
		88666 MK03_RAT (29-383): 1.6e-133: 388: 35.93		D3ZN21_RAT (151-758): 4.07e-141: 432: 31.88
+	Hs
		133884 CDK2_HUMAN (35-344): 3.61e-134: 387: 32.80		DDX3X_HUMAN (151-743): 1.87e-141: 432: 33.33
+	Hs
		133769 MK13_HUMAN (30-383): 2.24e-132: 385: 38.20		DDX3X_HUMAN (151-743): 1.87e-141: 432: 33.33
+	Hs
		625535 CDK2_HUMAN (35-344): 3.61e-134: 387: 32.80		DDX17_HUMAN (281-742): 1.52e-137: 425: 32.83
+	Hs
		571371 MK10_HUMAN (8-384): 2.45e-132: 389: 49.07		DDX5_HUMAN (248-760): 4.08e-137: 420: 29.57
+	Hs
		571314 CDK2_HUMAN (35-344): 3.61e-134: 387: 32.80		DDX5_HUMAN (248-760): 4.08e-137: 420: 29.57
+	Sc
		624046 HOG1_YEAST (29-382): 7.25e-131: 384: 37.64		DBP2_YEAST (233-741): 3.25e-135: 412: 29.35
+	Ce
		218277 KGB1_CAEEL (1-390): 7.51e-140: 405: 100.00		GLH4_CAEEL (2-362): 1.66e-11: 70: 16.79
+	Ce
		218282 KGB1_CAEEL (1-390): 7.51e-140: 405: 100.00		GLH2_CAEEL (50-371): 4.18e-09: 62.3: 19.29
+	Hs
		659083 MK01_HUMAN (32-382): 1.99e-67: 219: 36.34		DDX41_HUMAN (339-736): 8.21e-71: 245: 37.84