HitPredict

Interactor 1: NH111 (O45521)
Nuclear hormone receptor family member nhr-111
Gene: nhr-111

Interactor 2: HSP1 (P09446)
Heat shock protein hsp-1 (Heat shock 70 kDa protein A)
Gene: hsp-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 311 Ce			1 640
+	Hs
		369084 ESR1_HUMAN (24-307): 1.21e-75: 244: 18.16		HS71L_HUMAN (2-640): 0: 953: 80.60
+	Hs
		503444 NR4A1_HUMAN (10-309): 1.74e-76: 246: 20.80		HSP7C_HUMAN (1-614): 0: 942: 86.32
+	Hs
		504003 NR1H3_HUMAN (1-311): 8.36e-78: 245: 17.45		HSP7C_HUMAN (1-614): 0: 942: 86.32
+	Hs
		368878 ESR1_HUMAN (24-307): 1.21e-75: 244: 18.16		HSP7C_HUMAN (1-614): 0: 942: 86.32
+	Hs
		368938 ESR1_HUMAN (24-307): 1.21e-75: 244: 18.16		HSP76_HUMAN (2-640): 0: 942: 77.22
+	Hs
		487886 RARA_HUMAN (3-304): 2.36e-75: 239: 18.28		HSP7C_HUMAN (1-614): 0: 942: 86.32
+	Mm
		509285 RARA_MOUSE (6-304): 3.58e-75: 239: 18.16		HS71B_MOUSE (1-640): 0: 941: 80.09
+	Hs
		377052 GCR_HUMAN (1-307): 2.34e-70: 234: 17.16		HSP7C_HUMAN (1-614): 0: 942: 86.32
+	Hs
		714036 ESR2_HUMAN (28-307): 3.92e-68: 223: 19.55		HS71L_HUMAN (2-640): 0: 953: 80.60
+	Hs
		320162 ERR2_HUMAN (35-307): 5.63e-72: 230: 20.92		HSP7C_HUMAN (1-614): 0: 942: 86.32
+	Hs
		369248 ESR1_HUMAN (24-307): 1.21e-75: 244: 18.16		HSP72_HUMAN (2-640): 0: 925: 81.12
+	Hs
		504498 ESR2_HUMAN (28-307): 3.92e-68: 223: 19.55		HSP7C_HUMAN (1-614): 0: 942: 86.32
+	Hs
		564142 ESR2_HUMAN (28-307): 3.92e-68: 223: 19.55		HSP76_HUMAN (2-640): 0: 942: 77.22
+	Hs
		487079 ANDR_HUMAN (38-301): 6.08e-61: 210: 20.42		HSP7C_HUMAN (1-614): 0: 942: 86.32
+	Hs
		503668 NR2C2_HUMAN (25-117): 2.18e-21: 96.3: 43.14		HSP7C_HUMAN (1-614): 0: 942: 86.32
+	Dm
		505045 USP_DROME (41-117): 6.74e-23: 100: 54.55		HSP7D_DROME (1-613): 0: 927: 84.18