Interactor 1: PTEN (O54857)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Phosphatase and tensin homolog)
Gene: PTEN

Interactor 2: 5HT2C (P08909)
5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)
Gene: Htr2c

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 23345234
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0007626 - locomotory behavior
GO:0009410 - response to xenobiotic stimulus
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 403
Rn

1 460
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024