HitPredict

Interactor 1: ITB3 (O54890)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: Itgb3

Interactor 2: CSK (P41241)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase MPK-2) (p50CSK)
Gene: CSK

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24558484
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005911 - cell-cell junction GO:0046872 - metal ion binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 787 Mm			1 450
+	Mm
		222493 ITB3_MOUSE (1-787): 0: 793: 100.00		SRC_MOUSE (12-442): 1.78e-169: 488: 40.00
+	Rn
		989766 ITB3_RAT (1-787): 0: 789: 96.19		LYN_RAT (4-445): 7.88e-162: 468: 37.69
+	Hs
		396559 ITB3_HUMAN (1-787): 0: 763: 90.61		SRC_HUMAN (12-442): 8.06e-171: 491: 39.78
+	Hs
		396551 ITB3_HUMAN (1-787): 0: 763: 90.61		LYN_HUMAN (4-445): 1.69e-161: 467: 37.91
+	Mm
		337617 ITB1_MOUSE (10-786): 0: 733: 43.27		ABL1_MOUSE (5-446): 4.66e-165: 495: 38.14
+	Mm
		447063 ITB1_MOUSE (10-786): 0: 733: 43.27		FGR_MOUSE (12-442): 1.12e-165: 478: 37.75
+	Mm
		435876 ITB1_MOUSE (10-786): 0: 733: 43.27		HCK_MOUSE (7-445): 4.83e-163: 471: 36.56
+	Hs
		403736 ITB1_HUMAN (10-786): 0: 728: 43.52		LYN_HUMAN (4-445): 1.69e-161: 467: 37.91
+	Hs
		337304 ITB2_HUMAN (26-785): 0: 650: 38.73		ABL1_HUMAN (5-446): 1.08e-164: 495: 38.14
+	Hs
		396605 ITB2_HUMAN (26-785): 0: 650: 38.73		LYN_HUMAN (4-445): 1.69e-161: 467: 37.91
+	Dm
		246709 TENM_DROME (624-726): 1.3e-15: 84: 15.60		ABL_DROME (5-446): 1.23e-163: 503: 38.63
+	Hs
		433503 TEN1_HUMAN (355-501): 1.87e-09: 63.6: 9.52		YES_HUMAN (12-442): 1.06e-170: 491: 37.75