Interactor 1: B2L11 (O54918)
Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)
Gene: Bcl2l11
Interactor 2: MCL1 (P97287)
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Bcl-2-related protein EAT/mcl1)
Gene: MCL1
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.84 | 1.00 | 0.920 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17289999, 15694340, 18589438, 20921992, 16543145 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation, surface plasmon resonance, isothermal titration calorimetry |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~Bclx_interact |
| Common GO terms | GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0008630 - intrinsic apoptotic signaling pathway in response to DNA damage GO:0016020 - membrane GO:0042981 - regulation of apoptotic process and 3 others more... |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
