Interactor 1: PER2 (O54943)
Period circadian protein homolog 2 (mPER2) (Circadian clock protein PERIOD 2)
Gene: PER2

Interactor 2: PER2 (O54943)
Period circadian protein homolog 2 (mPER2) (Circadian clock protein PERIOD 2)
Gene: PER2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.910

The method score is based on:

Property Details
Experiments 26903623, 20211142, 19402751, 24737000
Identification Methods affinity chromatography technology, two hybrid, molecular sieving, anti tag coimmunoprecipitation, cosedimentation in solution, x-ray crystallography, two hybrid array
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PAS_3~PAS_3
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001222 - transcription corepressor binding
GO:0002931 - response to ischemia
and 36 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1257
Mm

1 1257
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Last updated: 15 Jul 2024