Protein: IDH3A
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha)

Gene: IDH3A
Organism: Homo sapiens
Interactions: 75
UniProt ID: P50213

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004449 - isocitrate dehydrogenase (NAD+) activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

215973

IDH3B
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial

5

12

Small-scale

0.927

High

837719

IDH3G
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

5

13

Small-scale

0.924

High

837718

IDH3A
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

12

High-throughput

0.618

High

226872

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

837736

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

2

High-throughput

0.584

High

837755

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.541

High

346248

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.536

High

528783

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

837744

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

837724

DMWD
Dystrophia myotonica WD repeat-containing protein

1

9

High-throughput

0.515

High

336419

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

452679

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

677901

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.513

High

300083

PRP6
Pre-mRNA-processing factor 6

1

2

High-throughput

0.481

High

837735

SF01
Splicing factor 1

1

1

High-throughput

0.481

High

338133

EGFR
Epidermal growth factor receptor

1

4

High-throughput

0.479

High

428974

ADRB2
Beta-2 adrenergic receptor

1

3

High-throughput

0.479

High

569399

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

650685

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

684523

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.479

High

713437

GLYC
Serine hydroxymethyltransferase, cytosolic

1

1

Small-scale

0.479

High

777505

MDHM
Malate dehydrogenase, mitochondrial

1

5

High-throughput

0.479

High

779028

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

837720

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.479

High

837722

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.479

High

837725

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

837726

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

1

High-throughput

0.479

High

837727

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

837728

CUL3
Cullin-3

1

1

High-throughput

0.479

High

837732

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

837733

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.479

High

837734

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.479

High

837746

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

837747

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

837751

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.479

High

837753

MTG2
Mitochondrial ribosome-associated GTPase 2

1

1

High-throughput

0.479

High

837756

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

837759

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

837760

UBQL2
Ubiquilin-2

1

2

High-throughput

0.479

High

381866

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.458

High

417199

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

622404

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.458

High

789715

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

799185

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

837721

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

Small-scale

0.458

High

837723

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

837739

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

837743

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

837748

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

837757

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

837761

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.458

High

977

SIM26
Small integral membrane protein 26

1

1

High-throughput

0.445

High

496576

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.445

High

837731

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

1

Small-scale

0.445

High

837738

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

100599

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

719982

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

823704

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

837730

CUL7
Cullin-7

1

1

High-throughput

0.437

High

837737

CL16A
Protein CLEC16A

1

2

High-throughput

0.437

High

837740

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.437

High

837741

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

837745

RDH13
Retinol dehydrogenase 13

1

2

High-throughput

0.437

High

837754

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

591771

RAB4A
Ras-related protein Rab-4A

1

0

High-throughput

0.282

High

837742

KDM3B
Lysine-specific demethylase 3B

1

0

High-throughput

0.279

Low

837750

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.279

Low

48008

TM129
E3 ubiquitin-protein ligase TM129

1

0

High-throughput

0.249

Low

322345

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

837729

RBM39
RNA-binding protein 39

1

0

High-throughput

0.249

Low

837749

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.249

Low

837758

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.249

Low

377989

PRIO
Major prion protein

1

0

High-throughput

0.232

Low

837752

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024