Interactor 1: PER2 (O54943)
Period circadian protein homolog 2 (mPER2) (Circadian clock protein PERIOD 2)
Gene: PER2

Interactor 2: BMAL1 (Q9WTL8)
Basic helix-loop-helix ARNT-like protein 1 (Arnt3) (Aryl hydrocarbon receptor nuclear translocator-like protein 1) (Brain and muscle ARNT-like 1)
Gene: BMAL1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.957

The method score is based on:

Property Details
Experiments 14701732, 16717091, 22274616, 26903623, 21680841, 16777965, 18430226, 20832105
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, gal4 vp16 complementation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PAS~PAS_3, PAS_11~PAS_3
Common GO terms GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 7 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1257
Mm

1 632
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Last updated: 15 Jul 2024