HitPredict

Interactor 1: SYUA (O55042)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: Snca

Interactor 2: VAMP2 (P63044)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

The method score is based on:

Property	Details
Experiments	21151134, 20798282
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000149 - SNARE binding GO:0005543 - phospholipid binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0008021 - synaptic vesicle and 7 others more... GO:0030659 - cytoplasmic vesicle membrane GO:0030672 - synaptic vesicle membrane GO:0035493 - SNARE complex assembly GO:0045202 - synapse GO:0048471 - perinuclear region of cytoplasm GO:0048488 - synaptic vesicle endocytosis GO:0060291 - long-term synaptic potentiation
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	140
Mm

1	116

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024