Protein: ASPP2
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)

Gene: ASPP2, TP53BP2
Organism: Homo sapiens
Interactions: 234
UniProt ID: Q13625

Gene Ontology (top 5):
GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

386699

P53
Cellular tumor antigen p53

11

17

Small-scale

0.979

High

200217

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

3

7

High-throughput

0.861

High

489414

BCL2
Apoptosis regulator Bcl-2

2

4

Small-scale

0.839

High

992073

B2CL1
Bcl-2-like protein 1

2

4

Small-scale

0.826

High

978748

TF65
Transcription factor p65

2

12

Small-scale

0.825

High

883334

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

13

High-throughput

0.817

High

1043772

BAIP2
BAR/IMD domain-containing adapter protein 2

2

13

High-throughput

0.817

High

1043718

B2CL2
Bcl-2-like protein 2

2

4

Small-scale

0.799

High

737795

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

13

20

Small-scale

0.763

High

905884

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

13

20

Small-scale

0.762

High

808586

YAP1
Transcriptional coactivator YAP1

12

20

Small-scale

0.760

High

802592

CRK
Adapter molecule crk

2

15

High-throughput

0.757

High

919068

RAN
GTP-binding nuclear protein Ran

1

9

Small-scale

0.757

High

1043774

NINL
Ninein-like protein

2

14

High-throughput

0.754

High

1043655

ASPP2
Apoptosis-stimulating of p53 protein 2

1

19

Small-scale

0.748

High

924553

GRB2
Growth factor receptor-bound protein 2

1

18

High-throughput

0.740

High

1043708

RASF8
Ras association domain-containing protein 8

6

12

High-throughput

0.737

High

906447

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

5

20

High-throughput

0.728

High

981992

1433F
14-3-3 protein eta

5

20

High-throughput

0.716

High

1043710

PARD3
Partitioning defective 3 homolog

5

18

Small-scale

0.711

High

972967

RASF7
Ras association domain-containing protein 7

4

12

High-throughput

0.699

High

904539

1433G
14-3-3 protein gamma

4

20

High-throughput

0.699

High

927020

1433Z
14-3-3 protein zeta/delta

4

20

High-throughput

0.694

High

1043662

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

14

High-throughput

0.691

High

1043746

PAR6B
Partitioning defective 6 homolog beta

1

3

High-throughput

0.691

High

1043759

PAR6A
Partitioning defective 6 homolog alpha

1

5

High-throughput

0.691

High

683330

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.678

High

909538

1433E
14-3-3 protein epsilon

3

6

High-throughput

0.671

High

1043702

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

3

7

High-throughput

0.670

High

154957

NDC80
Kinetochore protein NDC80 homolog

3

13

High-throughput

0.669

High

1043692

HOME1
Homer protein homolog 1

3

11

High-throughput

0.667

High

1043735

FRMD6
FERM domain-containing protein 6

3

20

High-throughput

0.667

High

903713

LMO4
LIM domain transcription factor LMO4

1

20

High-throughput

0.662

High

861746

PLK1
Serine/threonine-protein kinase PLK1

1

9

High-throughput

0.656

High

1032901

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

9

High-throughput

0.656

High

175874

P73
Tumor protein p73

1

17

Small-scale

0.647

High

475731

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

7

High-throughput

0.647

High

1043752

P63
Tumor protein 63

1

17

Small-scale

0.647

High

1043728

SGF29
SAGA-associated factor 29

3

0

High-throughput

0.638

High

1043731

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

12

Small-scale

0.634

High

770587

TXLNA
Alpha-taxilin

2

13

High-throughput

0.633

High

1043695

SIAH1
E3 ubiquitin-protein ligase SIAH1

2

11

High-throughput

0.633

High

1043706

MTMRE
Myotubularin-related protein 14

2

1

High-throughput

0.633

High

1043712

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

3

High-throughput

0.633

High

1043727

OTUB2
Ubiquitin thioesterase OTUB2

2

1

High-throughput

0.633

High

1043773

ADIP
Afadin- and alpha-actinin-binding protein

2

2

High-throughput

0.631

High

646875

1433T
14-3-3 protein theta

2

20

High-throughput

0.629

High

1043771

PRP19
Pre-mRNA-processing factor 19

2

11

High-throughput

0.628

High

1043673

CCD92
Coiled-coil domain-containing protein 92

2

1

High-throughput

0.628

High

170651

AXIN1
Axin-1

1

11

High-throughput

0.621

High

303759

DIRA1
GTP-binding protein Di-Ras1

1

7

High-throughput

0.621

High

339242

MOS
Proto-oncogene serine/threonine-protein kinase mos

1

1

High-throughput

0.621

High

640471

DDX6
Probable ATP-dependent RNA helicase DDX6

1

5

High-throughput

0.621

High

669168

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

20

High-throughput

0.621

High

874277

GEM
GTP-binding protein GEM

1

5

High-throughput

0.621

High

1043658

ARHG6
Rho guanine nucleotide exchange factor 6

1

9

High-throughput

0.621

High

1043687

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

10

High-throughput

0.621

High

1043711

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

15

High-throughput

0.621

High

1043721

LHX4
LIM/homeobox protein Lhx4

1

20

High-throughput

0.621

High

1043723

SH3K1
SH3 domain-containing kinase-binding protein 1

1

17

High-throughput

0.621

High

1043769

DP13A
DCC-interacting protein 13-alpha

1

4

High-throughput

0.621

High

325722

LATS1
Serine/threonine-protein kinase LATS1

1

14

High-throughput

0.618

High

507987

FGFR1
Fibroblast growth factor receptor 1

1

15

High-throughput

0.618

High

784004

KPCI
Protein kinase C iota type

1

9

Small-scale

0.618

High

835365

GSK3A
Glycogen synthase kinase-3 alpha

1

14

High-throughput

0.618

High

835735

GSK3B
Glycogen synthase kinase-3 beta

1

16

High-throughput

0.618

High

990837

ZO1
Tight junction protein ZO-1

1

16

High-throughput

0.618

High

1036557

SQSTM
Sequestosome-1

1

12

High-throughput

0.618

High

1043664

ZYX
Zyxin

1

12

High-throughput

0.618

High

1043693

MIB1
E3 ubiquitin-protein ligase MIB1

1

20

High-throughput

0.618

High

1043754

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

1043761

LATS2
Serine/threonine-protein kinase LATS2

1

13

High-throughput

0.618

High

1043768

ZO2
Tight junction protein ZO-2

1

8

High-throughput

0.618

High

63647

RASFA
Ras association domain-containing protein 10

2

4

High-throughput

0.614

High

125441

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

12

High-throughput

0.611

High

717064

CTNB1
Catenin beta-1

2

13

Small-scale

0.611

High

1043762

TB22B
TBC1 domain family member 22B

3

3

High-throughput

0.606

High

521917

CADH1
Cadherin-1

2

4

Small-scale

0.594

High

232156

KDM1A
Lysine-specific histone demethylase 1A

2

10

High-throughput

0.586

High

1043660

PCM1
Pericentriolar material 1 protein

2

1

High-throughput

0.584

High

1043671

AMOT
Angiomotin

2

20

High-throughput

0.584

High

1043701

NIN
Ninein

2

19

High-throughput

0.584

High

1043750

WWTR1
WW domain-containing transcription regulator protein 1

2

20

Small-scale

0.584

High

199114

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

13

Small-scale

0.578

High

1043670

PKHN1
Pleckstrin homology domain-containing family N member 1

2

5

High-throughput

0.578

High

1043700

PALS1
Protein PALS1

1

3

High-throughput

0.575

High

1043685

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

2

High-throughput

0.574

High

563753

ZNF26
Zinc finger protein 26

1

2

High-throughput

0.573

High

880302

TCL1A
T-cell leukemia/lymphoma protein 1A

1

2

High-throughput

0.573

High

918345

H2B1C
Histone H2B type 1-C/E/F/G/I

1

16

High-throughput

0.573

High

1043669

C19L2
CWF19-like protein 2

1

1

High-throughput

0.573

High

1043691

NUTM1
NUT family member 1

1

1

High-throughput

0.573

High

1043703

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

1

1

High-throughput

0.573

High

1043741

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

13

High-throughput

0.573

High

1043742

TRAF4
TNF receptor-associated factor 4

1

20

High-throughput

0.573

High

1043767

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.573

High

1043737

CC85A
Coiled-coil domain-containing protein 85A

2

10

High-throughput

0.560

High

1043705

IQUB
IQ motif and ubiquitin-like domain-containing protein

1

1

High-throughput

0.555

High

1043756

PKHF2
Pleckstrin homology domain-containing family F member 2

1

12

High-throughput

0.555

High

1043757

UBTD1
Ubiquitin domain-containing protein 1

1

1

High-throughput

0.555

High

808118

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

12

Small-scale

0.554

High

330161

APCL
Adenomatous polyposis coli protein 2

1

20

Small-scale

0.552

High

921114

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.549

High

1043719

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.549

High

1043730

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.549

High

983121

UBE3A
Ubiquitin-protein ligase E3A

1

20

High-throughput

0.541

High

1017529

KIF5A
Kinesin heavy chain isoform 5A

1

2

High-throughput

0.541

High

1024328

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

8

High-throughput

0.541

High

1043743

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

2

High-throughput

0.541

High

1043763

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

18

Small-scale

0.536

High

277413

RASF9
Ras association domain-containing protein 9

1

11

High-throughput

0.536

High

280042

MPDZ
Multiple PDZ domain protein

1

17

High-throughput

0.536

High

323742

BAG2
BAG family molecular chaperone regulator 2

1

7

High-throughput

0.536

High

376233

ANXA1
Annexin A1

1

2

High-throughput

0.536

High

714220

HSP74
Heat shock 70 kDa protein 4

1

17

High-throughput

0.536

High

869371

HAP1
Huntingtin-associated protein 1

1

6

High-throughput

0.536

High

871561

HSP72
Heat shock-related 70 kDa protein 2

1

11

High-throughput

0.536

High

916568

RS6
Small ribosomal subunit protein eS6

1

2

High-throughput

0.536

High

998681

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.536

High

1043657

BECN1
Beclin-1

1

2

High-throughput

0.536

High

1043663

CC85B
Coiled-coil domain-containing protein 85B

1

10

High-throughput

0.536

High

1043715

HS105
Heat shock protein 105 kDa

1

20

High-throughput

0.536

High

1043766

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

3

High-throughput

0.536

High

1043775

AMOL2
Angiomotin-like protein 2

1

20

High-throughput

0.536

High

394684

A4
Amyloid-beta precursor protein

1

4

Small-scale

0.529

High

587566

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

Small-scale

0.527

High

932688

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.518

High

1034152

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.518

High

559701

H12
Histone H1.2

1

6

High-throughput

0.515

High

1043659

PLEC
Plectin

1

12

High-throughput

0.515

High

1043734

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

173959

ATX7
Ataxin-7

1

15

High-throughput

0.508

High

931627

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.508

High

1043707

PPHLN
Periphilin-1

1

1

High-throughput

0.508

High

597388

PTN
Pleiotrophin

1

1

High-throughput

0.494

High

63755

CC85C
Coiled-coil domain-containing protein 85C

1

10

High-throughput

0.489

High

1043753

CPVL
Probable serine carboxypeptidase CPVL

1

1

High-throughput

0.489

High

1043776

EMIL1
EMILIN-1

1

7

High-throughput

0.489

High

49020

SHOT1
Shootin-1

1

2

High-throughput

0.481

High

197982

PHF1
PHD finger protein 1

1

4

High-throughput

0.481

High

212407

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

3

High-throughput

0.481

High

253005

HSF2B
Heat shock factor 2-binding protein

1

4

High-throughput

0.481

High

278441

SPF27
Pre-mRNA-splicing factor SPF27

1

2

High-throughput

0.481

High

324387

BAG3
BAG family molecular chaperone regulator 3

1

8

High-throughput

0.481

High

535389

GFAP
Glial fibrillary acidic protein

1

15

High-throughput

0.481

High

595216

LMNB1
Lamin-B1

1

15

High-throughput

0.481

High

659715

RXRB
Retinoic acid receptor RXR-beta

1

20

High-throughput

0.481

High

974249

HHEX
Hematopoietically-expressed homeobox protein HHEX

1

18

High-throughput

0.481

High

1017043

TROAP
Tastin

1

1

High-throughput

0.481

High

1028158

GPS2
G protein pathway suppressor 2

1

1

High-throughput

0.481

High

1043656

ELOA1
Elongin-A

1

19

High-throughput

0.481

High

1043661

RBP1
RalA-binding protein 1

1

13

High-throughput

0.481

High

1043668

CCD57
Coiled-coil domain-containing protein 57

1

11

High-throughput

0.481

High

1043672

CEP55
Centrosomal protein of 55 kDa

1

4

High-throughput

0.481

High

1043677

OTU1
Ubiquitin thioesterase OTU1

1

1

High-throughput

0.481

High

1043686

ZN438
Zinc finger protein 438

1

3

High-throughput

0.481

High

1043690

ZN575
Zinc finger protein 575

1

3

High-throughput

0.481

High

1043694

RASL3
RAS protein activator like-3

1

7

High-throughput

0.481

High

1043697

CCD13
Coiled-coil domain-containing protein 13

1

10

High-throughput

0.481

High

1043699

MTURN
Maturin

1

1

High-throughput

0.481

High

1043713

PIBF1
Progesterone-induced-blocking factor 1

1

5

High-throughput

0.481

High

1043716

CBP
CREB-binding protein

1

15

Small-scale

0.481

High

1043717

GOGA1
Golgin subfamily A member 1

1

8

High-throughput

0.481

High

1043720

H2B1H
Histone H2B type 1-H

1

16

High-throughput

0.481

High

1043726

GCC1
GRIP and coiled-coil domain-containing protein 1

1

11

High-throughput

0.481

High

1043729

CEP95
Centrosomal protein of 95 kDa

1

1

High-throughput

0.481

High

1043732

ZFP91
E3 ubiquitin-protein ligase ZFP91

1

6

High-throughput

0.481

High

1043740

CDC5L
Cell division cycle 5-like protein

1

6

High-throughput

0.481

High

1043744

SCNM1
Sodium channel modifier 1

1

4

High-throughput

0.481

High

1043747

TSG10
Testis-specific gene 10 protein

1

16

High-throughput

0.481

High

1043748

SETD5
Histone-lysine N-methyltransferase SETD5

1

17

High-throughput

0.481

High

1043755

ZN552
Zinc finger protein 552

1

5

High-throughput

0.481

High

1043764

ZBTB4
Zinc finger and BTB domain-containing protein 4

1

3

High-throughput

0.481

High

1043765

CING
Cingulin

1

6

High-throughput

0.481

High

230961

CE104
Centrosomal protein of 104 kDa

1

1

High-throughput

0.479

High

272557

OFD1
Centriole and centriolar satellite protein OFD1

1

9

High-throughput

0.479

High

302516

CE152
Centrosomal protein of 152 kDa

1

7

High-throughput

0.479

High

346730

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.479

High

436711

GLI1
Zinc finger protein GLI1

1

6

Small-scale

0.479

High

444366

K1C19
Keratin, type I cytoskeletal 19

1

9

High-throughput

0.479

High

552677

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

651153

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

684021

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

716675

CTNA1
Catenin alpha-1

1

6

High-throughput

0.479

High

779377

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

781889

PERI
Peripherin

1

14

High-throughput

0.479

High

840470

VASP
Vasodilator-stimulated phosphoprotein

1

10

High-throughput

0.479

High

876378

AFAD
Afadin

1

20

High-throughput

0.479

High

891754

ACTB
Actin, cytoplasmic 1

1

6

High-throughput

0.479

High

1017624

STX4
Syntaxin-4

1

3

High-throughput

0.479

High

1026402

RFA4
Replication protein A 30 kDa subunit

1

7

High-throughput

0.479

High

1038358

HDAC1
Histone deacetylase 1

1

9

High-throughput

0.479

High

1039421

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

5

Small-scale

0.479

High

1043665

OCLN
Occludin

1

2

High-throughput

0.479

High

1043674

ODFP2
Outer dense fiber protein 2

1

7

High-throughput

0.479

High

1043676

CE162
Centrosomal protein of 162 kDa

1

13

High-throughput

0.479

High

1043678

CP135
Centrosomal protein of 135 kDa

1

12

High-throughput

0.479

High

1043679

FTM
Protein fantom

1

19

High-throughput

0.479

High

1043682

SYNE3
Nesprin-3

1

13

High-throughput

0.479

High

1043688

CNTRL
Centriolin

1

11

High-throughput

0.479

High

1043689

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

1043696

CEP97
Centrosomal protein of 97 kDa

1

8

High-throughput

0.479

High

1043698

CNTRB
Centrobin

1

9

High-throughput

0.479

High

1043704

CE120
Centrosomal protein of 120 kDa

1

16

High-throughput

0.479

High

1043709

FBF1
Fas-binding factor 1

1

13

High-throughput

0.479

High

1043724

PF21A
PHD finger protein 21A

1

16

High-throughput

0.479

High

1043725

ENTR1
Endosome-associated-trafficking regulator 1

1

3

High-throughput

0.479

High

1043736

SCLT1
Sodium channel and clathrin linker 1

1

13

High-throughput

0.479

High

1043739

CEP89
Centrosomal protein of 89 kDa

1

8

High-throughput

0.479

High

1043749

CEP44
Centrosomal protein of 44 kDa

1

2

High-throughput

0.479

High

1043751

ATG5
Autophagy protein 5

1

2

Small-scale

0.479

High

1043758

CENPJ
Centromere protein J

1

10

High-throughput

0.479

High

1043760

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.479

High

1043770

RCOR1
REST corepressor 1

1

12

High-throughput

0.479

High

928595

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.458

High

1043681

Q6NSK7
RIN3 protein

1

5

High-throughput

0.457

High

151795

IRS4
Insulin receptor substrate 4

1

3

Small-scale

0.445

High

834597

NU153
Nuclear pore complex protein Nup153

1

20

Small-scale

0.445

High

903810

NTF2
Nuclear transport factor 2

1

3

Small-scale

0.445

High

885643

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

2

High-throughput

0.439

High

975651

LMNB2
Lamin-B2

1

15

High-throughput

0.439

High

1043675

EFHC1
EF-hand domain-containing protein 1

1

2

High-throughput

0.439

High

1043683

INSY2
Inhibitory synaptic factor 2A

1

1

High-throughput

0.439

High

1043722

RGMA
Repulsive guidance molecule A

1

2

High-throughput

0.439

High

1043738

PRAM
PML-RARA-regulated adapter molecule 1

1

14

High-throughput

0.439

High

1043666

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

2

High-throughput

0.437

High

1043680

RNF43
E3 ubiquitin-protein ligase RNF43

1

4

High-throughput

0.437

High

1043684

CE128
Centrosomal protein of 128 kDa

1

10

High-throughput

0.437

High

1043733

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

16

High-throughput

0.437

High

1043667

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

1

High-throughput

0.407

High

1043745

RM20
Large ribosomal subunit protein bL20m

1

0

High-throughput

0.282

High

782719

IPP2
Protein phosphatase inhibitor 2

1

0

High-throughput

0.279

Low

1043714

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024