HitPredict

Interactor 1: PSA7 (O59770)
Probable proteasome subunit alpha type-7
Gene: pre10

Interactor 2: RPN1 (P87048)
26S proteasome regulatory subunit rpn1 (19S regulatory cap region of 26S protease subunit 2) (Proteasome non-ATPase subunit mts4)
Gene: RPN1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28784663
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 253 Sp			1 891
+	Hs
		637679 PSA2_HUMAN (6-238): 8.16e-100: 292: 31.62		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Sp
		953217 PSA5_SCHPO (1-240): 1.24e-95: 282: 30.36		RPN1_SCHPO (1-891): 0: 1228: 100.00
+	Hs
		656214 PSA5_HUMAN (1-237): 1.45e-95: 281: 30.45		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Hs
		637871 PSA3_HUMAN (1-251): 7.19e-94: 278: 48.62		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Sp
		953201 PSA3_SCHPO (4-243): 5.82e-92: 272: 25.10		RPN1_SCHPO (1-891): 0: 1228: 100.00
+	Hs
		893662 PSA6_HUMAN (4-241): 1.41e-91: 271: 29.63		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Dm
		1360089 PSA3_DROME (1-248): 2.13e-99: 292: 42.40		Q9VW54_DROME (41-885): 0: 1064: 46.89
+	Dm
		1278652 PSA5_DROME (1-238): 4.48e-95: 280: 29.68		Q9VW54_DROME (41-885): 0: 1064: 46.89
+	Sc
		597233 PSA7_YEAST (1-244): 1.72e-108: 316: 55.02		RPN1_YEAST (50-885): 0: 901: 39.42
+	Hs
		637734 PSA2_HUMAN (6-238): 8.16e-100: 292: 31.62		PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43
+	Hs
		656297 PSA5_HUMAN (1-237): 1.45e-95: 281: 30.45		PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43
+	Hs
		637988 PSA3_HUMAN (1-251): 7.19e-94: 278: 48.62		PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43
+	Hs
		893734 PSA6_HUMAN (4-241): 1.41e-91: 271: 29.63		PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43
+	Sc
		597216 PSA7_YEAST (1-244): 1.72e-108: 316: 55.02		RPN2_YEAST (60-822): 4.16e-145: 455: 18.37
+	Dm
		1359003 PSA3_DROME (1-248): 2.13e-99: 292: 42.40		PSMD1_DROME (370-819): 2.85e-141: 447: 21.91
+	Hs
		686 PSA2_HUMAN (6-238): 8.16e-100: 292: 31.62		A0A087WW66_HUMAN (141-826): 6.93e-140: 440: 18.87
+	Dm
		1278636 PSA5_DROME (1-238): 4.48e-95: 280: 29.68		PSMD1_DROME (370-819): 2.85e-141: 447: 21.91
+	Hs
		689 PSA5_HUMAN (1-237): 1.45e-95: 281: 30.45		A0A087WW66_HUMAN (141-826): 6.93e-140: 440: 18.87
+	Hs
		687 PSA3_HUMAN (1-251): 7.19e-94: 278: 48.62		A0A087WW66_HUMAN (141-826): 6.93e-140: 440: 18.87
+	Hs
		699 PSA6_HUMAN (4-241): 1.41e-91: 271: 29.63		A0A087WW66_HUMAN (141-826): 6.93e-140: 440: 18.87